Description Usage Arguments Details Value Author(s) References See Also Examples
Given a set of SNPs, computes a matrix of r2
1 | r2fast.old(data, snpsubset, idsubset)
|
data |
object of |
snpsubset |
Index, character or logical vector with subset of SNPs to run analysis on.
If missing, all SNPs from |
idsubset |
Index, character or logical vector with subset of IDs to run analysis on.
If missing, all people from |
The function is based on slightly modified code of Hao et al.
A (Nsnps X Nsnps) matrix giving r2 values between a pairs of SNPs above the diagonal and number of SNP genotype measured for both SNPs below the diagonal
Yurii Aulchenko
Hao K, Di X, Cawley S. (2006) LdCompare: rapid computation of single- and multiple-marker r2 and genetic coverage. Bioinformatics, 23: 252-254.
1 2 3 4 5 6 7 8 9 10 11 12 13 | require(GenABEL.data)
data(ge03d2)
# r2s using r2fast.old
a <- r2fast.old(ge03d2,snps=c(1:10))
## Not run:
library(genetics)
# r2s using package genetics
b <- LD(as.genotype(ge03d2[,1:10]))$"R^2"
# see that the r2s are not exactly the same
cor(a[upper.tri(a)],b[upper.tri(b)])
plot(a[upper.tri(a)],b[upper.tri(b)])
## End(Not run)
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