mouse2human_eset: Convert Mouse Gene Symbols to Human Gene Symbols

In IOBR: Immune Oncology Biological Research

Convert Mouse Gene Symbols to Human Gene Symbols

Description

Converts mouse gene symbols to human gene symbols in an expression dataset. Supports using either an online resource (Ensembl) or a local dataset for conversion.

Usage

mouse2human_eset(
  eset,
  source = c("local", "ensembl"),
  is_matrix = TRUE,
  column_of_symbol = NULL,
  verbose = FALSE
)

Arguments

eset	Matrix or data frame. Expression matrix with genes in rows.
source	Character. Data source for conversion: "ensembl" (online) or "local". Default is "ensembl". If Ensembl fails, use "local" which uses the internal 'mus_human_gene_symbol' dataset.
is_matrix	Logical. Whether 'eset' is a matrix with gene symbols as row names. Default is 'TRUE'. If 'FALSE', 'column_of_symbol' must be specified.
column_of_symbol	Character or 'NULL'. Column name containing gene symbols if 'eset' is not a matrix. Default is 'NULL'.
verbose	Logical. If 'TRUE', prints available Ensembl datasets. Default is 'FALSE'.

Value

Expression set with human gene symbols.

Author(s)

Dongqiang Zeng

Examples

## Not run: 
set.seed(123)
data <- matrix(runif(50 * 3), nrow = 50, ncol = 3)
rownames(data) <- c("Tpt1", "Hmgb1", "Gapdh", paste0("Gene", 4:50))
colnames(data) <- paste0("Sample", 1:3)
human_data <- mouse2human_eset(data, source = "local", is_matrix = TRUE)
if (!is.null(human_data)) head(human_data)

## End(Not run)

IOBR documentation built on May 30, 2026, 5:07 p.m.