sig_group: Grouped gene signatures for IOBR analysis
In IOBR: Immune Oncology Biological Research

sig_group

R Documentation

Grouped gene signatures for IOBR analysis

Description

A named list that organizes gene signatures into functional or biological categories. Each element of the list is a character vector containing the names of gene signatures defined in signature_collection. A total of 43 signature groups are included, covering tumour intrinsic pathways, immune-related processes, stromal activity, TME characteristics and immuno-oncology biomarkers. These groups are used in IOBR to conveniently select sets of signatures for scoring and visualization.

Usage

data(sig_group)

Format

A named list of length 43. Each element is a character vector of signature names. Representative groups include:

tumor_signature: Signatures related to intrinsic tumour biology such as cell cycle, DNA damage repair and histone regulation.
EMT: Epithelial–mesenchymal transition (EMT)–associated signatures.
io_biomarkers: Immuno-oncology biomarker–related signatures.
immu_microenvironment: Immune microenvironment–related signatures.
immu_suppression: Immune suppression–related signatures.
immu_exclusion: Signatures associated with immune exclusion and stromal barriers.
TCR_BCR: T-cell and B-cell receptor pathway signatures.
tme_signatures1: Tumour microenvironment signature panel (set 1).
tme_signatures2: Tumour microenvironment signature panel (set 2).
...: Additional groups are included (43 total), but not listed individually here; all groups follow the same structure.