signature_collection: Gene signature collection for pathway and immune analysis

In IOBR: Immune Oncology Biological Research

Gene signature collection for pathway and immune analysis

Description

A named list of gene signatures used in the IOBR package for immune deconvolution, pathway scoring, functional annotation, and tumour microenvironment (TME) characterization. Each element corresponds to a predefined biological signature and contains a character vector of HGNC gene symbols.

Usage

data(signature_collection)

Format

A named list of length 323. Each element is a character vector of gene symbols. Representative entries include:

CD_8_T_effector

Markers of CD8^{+} effector T cells.

DDR

DNA damage response and repair genes.

Immune_Checkpoint

Immune checkpoint molecules.

CellCycle_Reg

Core regulators of cell-cycle progression.

Mismatch_Repair

Mismatch-repair pathway genes.

TMEsocreA_CIR

TME-related signature used in TMEscore analysis.

...

Additional signatures are included in the list but are not individually listed here; all follow the same structure.

Examples

data(signature_collection)
head(signature_collection)

IOBR documentation built on May 30, 2026, 5:07 p.m.