getCoExpGeneofLncs: Get Co-expressed Genes of LncRNAs

In LncPriCNet: Prioritizing Candidate LncRNAs Based on a Composite Multi-Level Network

Description

Get co-expressed genes of one or some lncRNAs based on the multi-omics network.

Usage

getCoExpGeneofLncs(lncRNAs, GLNet, scoreCutoff = 0.6)

Arguments

lncRNAs	A character or a character vector. The names of lncRNAs.
GLNet	An adjacency matrix of the gene-lncRNA network with colnames representing lncRNAs and rownames representing genes. The value represents co-expression relation and it ranges from 0 to 1.
scoreCutoff	A numeric donotes if the co-expression scores between genes and lncRNAs above this value, the genes would be retained. A value ranges from 0 to 1. The default value is 0.6.

Value

A vector of gene names.

Author(s)

Qianlan Yao <[e-mail]>

See Also

getTopDiseaseLncRNAs

Examples

## Not run: 
#############    getCoExpGeneofLncs   ################
##breast cancer 
data("GLNetExample")
diseaseInf<-getDiseaseInf("114480")
lncRNA<-diseaseInf$LncRNAs[1]
genes<-getCoExpGeneofLncs(lncRNA, GLNet=GLNetExample, scoreCutoff = 0.6) 
print(genes[1:5])


## End(Not run)

LncPriCNet documentation built on May 29, 2017, 3:46 p.m.