get_DenoisedNet: Denoising Predicted Protein-Protein Interactions

In MACP: Macromolecular Assemblies from Co-Elution Profile (MACP)

Denoising Predicted Protein-Protein Interactions

Description

This function removes the noise in the form of false positive edges in the predicted networks using network topology.

Usage

get_DenoisedNet(ppi)

Arguments

ppi	Interactions data containing id1-id2-weight triplets.

Details

get_DenoisedNet

Value

A data.frame containing denoised network.

Author(s)

Matineh Rahmatbakhsh, [e-mail]

Examples

# high-confidence network as input
ppi <-
read.table(system.file("extdata/ppi_input_ClusterONE.txt",
package="MACP"),
quote="\"", comment.char="")
# Perform network denoising
denoisetNet <- get_DenoisedNet(ppi)

MACP documentation built on March 7, 2023, 7:42 p.m.