subcellular.mtPPI: Keep Mitochondrial (mt) Proteins

In MACP: Macromolecular Assemblies from Co-Elution Profile (MACP)

Keep Mitochondrial (mt) Proteins

Description

This function removes PPIs occurring between outer mt membrane (OMM) and matrix, between intermembrane space (IMS) and matrix, as well as between any subcellular mt compartment (except OMM) and cytosolic proteins as they deemed to be erroneous

Usage

subcellular.mtPPI(ppi, organism = "mouse")

Arguments

ppi	Interactions data containing id1-id2-weight triplets.
organism	Organism under study (i.e., mouse or human). Defaults to mouse.

Details

subcellular.mtPPI

Value

Filtered PPI netwrok.

Author(s)

Matineh Rahmatbakhsh, [e-mail]

Examples

ppi <-
read.table(system.file("extdata/ppi_input_ClusterONE.txt",
package="MACP"),
quote="\"", comment.char="")
filtered_mtEdges <- subcellular.mtPPI(ppi)

MACP documentation built on March 7, 2023, 7:42 p.m.