Fit one OxyBS result

Description

Uses maximum likelihood to estimate (C,5mC,5hmC) for one CpG and one specimen

Usage

1
fitOneOxBS(betaBS, betaOxBS, signalBS, signalOxBS, eps=1E-5)

Arguments

betaBS

beta value from conventional bisulfite conversion

betaOxBS

beta value from oxy-bisulfite conversion

signalBS

total signal from conventional bisulfite conversion

signalOxBS

total signal from oxy-bisulfite conversion

eps

small positive value representing numerical zero

Details

Uses maximum likelihood to estimate (C,5mC,5hmC) for one CpG and one specimen; not typically called by user.

Value

(C,5mC,5hmC) for one CpG and one specimen.

Author(s)

E. Andres Houseman

See Also

fitOxBS