PAGI: The package can identify the dysregulated KEGG pathways based on global influence from the internal effect of pathways and crosstalk between pathways.

The package can identify the dysregulated KEGG pathways based on global influence from the internal effect of pathways and crosstalk between pathways. (1) The PAGI package can prioritize the pathways associated with two biological states by statistical significance or FDR. (2) The PAGI package can evaluated the global influence factor (GIF) score in the global gene-gene network constructed based on the relationships of genes extracted from each pathway in KEGG database and the overlapped genes between pathways.

Getting started

Package details

AuthorJunwei Han,Yanjun Xu,Haixiu Yang,Chunquan Li and Xia Li
Bioconductor views Graphs Networks Pathways Statistics crosstalk
MaintainerJunwei Han <hanjunwei1981@163.com>
LicenseGPL (>= 2)
Version1.0
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("PAGI")

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PAGI documentation built on May 1, 2019, 7:48 p.m.