Real.1-data: Real Dataset #1: Clinical Dataset (p < n case)

Description Usage Format Acknowledgments Author(s) Source References See Also

Description

Publicly available HIV clinical data from the Women's Interagency HIV cohort Study (WIHS). The entire study enrolled 1164 women. Inclusion criteria of the study are: women at enrolment must be (i) alive, (ii) HIV-1 infected, and (iii) free of clinical AIDS symptoms. Women were followed until the first of the following occurred: (i) treatment initiation (HAART), (ii) AIDS diagnosis, (iii) death, or administrative censoring. The studied outcomes were the competing risks "AIDS/Death (before HAART)" and "Treatment Initiation (HAART)". However, for simplification purposes, only the first of the two competing events (i.e. the time to AIDS/Death), was used. Likewise, for simplification in this clinical dataset example, only complete cases were used. Variables included history of Injection Drug Use ("IDU") at enrollment, African American ethnicity ('Race'), age ('Age'), and baseline CD4 count ('CD4') for a total of p=4 clinical covariates. The question in this dataset example was whether it is possible to achieve a prognostication of patients for AIDS and HAART. See Bacon et al. (2005) and the WIHS website for more details.

Usage

1

Format

Dataset consists of a numeric data.frame containing n=485 complete observations (samples) by rows and p=4 clinical covariates by columns, not including the censoring indicator and (censored) time-to-event variables. It comes as a compressed Rda data file.

Acknowledgments

This work made use of the High Performance Computing Resource in the Core Facility for Advanced Research Computing at Case Western Reserve University. This project was partially funded by the National Institutes of Health NIH - National Cancer Institute (R01-CA160593) to J-E. Dazard and J.S. Rao.

Author(s)

Maintainer: "Jean-Eudes Dazard, Ph.D." jean-eudes.dazard@case.edu

Source

See real data application in Dazard et al., 2015.

References

See Also

Women's Interagency HIV cohort Study website: https://statepi.jhsph.edu/wihs/wordpress/


PRIMsrc documentation built on Aug. 8, 2017, 1:06 a.m.