BMT: Bone Marrow Transplantation.

BMTR Documentation

Bone Marrow Transplantation.

Description

A simplified version of the data set printed in Klein and Moeschberger, 2003. Briefly, these data are from a study of 137 patients with acute myelocytic leukemia (AML) or acute lymphoblastic leukemia (ALL) aged 7 to 52 from four centres. Failure time is defined as the time (in days) to relapse or death.

Usage

BMT

Format

A data frame with 137 observations on the following 3 variables.

group

Categorisation of the patients' Leukemia (ALL = Acute Lymphoblastic Leukemia, AML-High Risk = High risk Acute Myelocytic Leukemia, AML-Low Risk = Low risk Acute Myelocytic Leukemia).

time

Failure time, defined as time (in days) to relapse or death.

status

Disease-free survival indicator (1 = Dead or Relapsed, 0 = Alive Disease Free).

Details

Bone marrow transplants are a standard treatment for acute leukemia.Recovery following bone marrow transplantation is a complex process and prognosis may depend on a number of different risk factors. Transplantation can be considered a failure when a patient's leukemia returns (relapse) or when he or she dies while in remission (treatment related death).

Source

Klein, J.P. and Moeschberger, M.L., 2003. Survival analysis: techniques for censored and truncated data (Vol. 1230). New York: Springer.

References

see also

Copelan,Biggs, Thompson, et al, Treatment for Acute Myelocytic Leukemia With Allogeneic Bone Marrow Transplantation Following Preparation With BuCy2, Blood, Volume 78, Issue 3, 1991, Pages 838-843, ISSN 0006-4971,

and

https://www.medicine.mcgill.ca/epidemiology/hanley/bios602/Klein-Moeschberger/Klein-Moeschberger-ch01.pdf

Examples

data(BMT, package = "R4HCR")



R4HCR documentation built on Sept. 30, 2024, 9:46 a.m.

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