SimData: Simulated example data

In SATS: Signature Analyzer for Targeted Sequencing (SATS)

Simulated example data

Description

Simulated data used in SATS examples and tests.

Details

This file consists of the list SimData with the following objects:

• V : Simulated mutation-count matrix of size 96 by 10027 generated from a Poisson distribution with mean corresponding to each element of L*(WH), where * denotes elementwise multiplication, L is the sample-level panel-context matrix below, W is the tumor mutation burden-normalized signature-profile matrix (TrueW_TMB below), and H is the signature-activity matrix (TrueH below).

• L : Sample-level panel-context matrix of size 96 by 10027.

• TrueH : Simulated signature-activity matrix of size 6 by 10027 used to generate V.

• TrueW_TMB : Tumor mutation burden-normalized signature-profile matrix of size 96 by 6 for 6 SBS signatures (SBS1, SBS2/13, SBS4, SBS5, SBS40, SBS89) used to generate V.

• SingleTumorEx : A single simulated tumor (column singleV) and its sequencing context (column singleL).

• PanelEx: An example sequencing panel information with Chromosome, Start_Position, End_Position, SEQ_ASSAY_ID.

• PatientInfo: An example patient data set containing patient IDs associated with SEQ_ASSAY_ID.

SATS documentation built on Sept. 16, 2026, 1:06 a.m.