SimData: Data for examples

In SATS: Signature Analyzer for Targeted Sequencing (SATS)

Data for examples

Description

Simulated data as an example

Details

This file consists of the list SimData with the following objects:

• V : Simulated mutation catalog matrix of size 96 by 10027 generated from the Poisson distribution with the mean corresponding to each element of L*(WH), where * is elementwise multiplication, L is the panel size matrix below, W is the profile matrix of the tumor mutation burden (TrueW_TMB below), and H is the signature activity matrix (TrueH below).

• L : Panel size matrix of size 96 by 10027.

• TrueH : Simulated signature activity matrix of size 6 by 10027 used to generate V.

• TrueW_TMB : Tumor mutation burden based signatures size 96 by 6 for 6 SBS signatures (SBS1, SBS2/13, SBS4, SBS5, SBS40, SBS89) used to generate V.

• SingleTumorEx : A single simulated tumor (column singleV) and its sequencing context (column singleL).

• PanelEx: An example data frame of panel information

SATS documentation built on Aug. 8, 2025, 6:22 p.m.