cat.heart: Cat Heart Data

cat.heartR Documentation

Cat Heart Data

Description

Data from a Latin square experiment on the potencies of cardiac drugs given to anesthetized cats.

Usage

data(cat.heart)

Format

A data frame with 64 observations on the following 6 variables.

Day

on which experiment performed

Time

morning or afternoon

Observer

four observers took part

Drug

cardiac drug given to cat

y

100 times log dose in micrograms at which cat died

x

100 times log cat heart weight in grams

Details

These are results from an experiment to determine the relative potencies of eight similar cardiac drugs, labelled A–H, where A is a standard. The method used was to infuse slowly a suitable dilution of the drug into an anaesthetized cat. The dose at which death occurred and the weight of the cat's heart were recorded. Four observers each made two determinations on each of eight days, with a Latin square design used to eliminate observer and time differences. The heart weight cannot be known at the start of the experiment, but might be expected to affect comparisons among the treatments; it is assumed that heart weight is unaffected by the treatments.

Source

Unpublished lecture notes, Imperial College, London.

References

Davison, A. C. (2003) Statistical Models. Cambridge University Press. Page 447.

Examples

data(cat.heart)
anova(lm(y~Observer+Time+Day+Drug+Observer:Time,data=cat.heart))

SMPracticals documentation built on May 29, 2024, 12:19 p.m.