cat.heart | R Documentation |
Data from a Latin square experiment on the potencies of cardiac drugs given to anesthetized cats.
data(cat.heart)
A data frame with 64 observations on the following 6 variables.
on which experiment performed
morning or afternoon
four observers took part
cardiac drug given to cat
100 times log dose in micrograms at which cat died
100 times log cat heart weight in grams
These are results from an experiment to determine the relative potencies of eight similar cardiac drugs, labelled A–H, where A is a standard. The method used was to infuse slowly a suitable dilution of the drug into an anaesthetized cat. The dose at which death occurred and the weight of the cat's heart were recorded. Four observers each made two determinations on each of eight days, with a Latin square design used to eliminate observer and time differences. The heart weight cannot be known at the start of the experiment, but might be expected to affect comparisons among the treatments; it is assumed that heart weight is unaffected by the treatments.
Unpublished lecture notes, Imperial College, London.
Davison, A. C. (2003) Statistical Models. Cambridge University Press. Page 447.
data(cat.heart)
anova(lm(y~Observer+Time+Day+Drug+Observer:Time,data=cat.heart))
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