SPINA.GDTT: Calculated Sum Activity of Step-Up Deiodinases (SPINA-GD)
In SPINA: Structure Parameter Inference Approach
Description
Usage
Arguments
Details
Value
Note
Author(s)
References
See Also
Description
Calculate total step-up deiodinase activity (SPINA-GD) from equilibrium total hormone concentrations. This is an alias for estimated.GDTT.
Usage
1
SPINA.GDTT(T4, T3)
Arguments
T4
Total thyroxine (TT4) concentration in nmol/L.
T3
Total triiodothyronine (TT3) concentation in pmol/L
Details
This function is able to do vectorised calculations.
Value
This function returns step-up deiodinase activity as a numeric result representing a single value or a vector, depending on the vector length of the arguments. Results are in nmol/s.
Note
The software functions described in this document are intended for research
use only. Hormone levels should have been obtained simultaneously in order to avoid
bias by transition effects.
Author(s)
Johannes W. Dietrich
References
Dietrich J. W., Landgrafe G., Fotiadou E. H. 2012 TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis. J Thyroid Res. 2012;2012:351864. doi: 10.1155/2012/351864. PMID: 23365787; PMCID: PMC3544290.
Dietrich J. W., Landgrafe-Mende G., Wiora E., Chatzitomaris A., Klein H. H., Midgley J. E., Hoermann R. 2016 Calculated Parameters of Thyroid Homeostasis: Emerging Tools for Differential Diagnosis and Clinical Research. Front Endocrinol (Lausanne). 2016 Jun 9;7:57. doi: 10.3389/fendo.2016.00057. PMID: 27375554; PMCID: PMC4899439.
See Also
SPINA.GT, estimated.GT, SPINA.GTT, estimated.GTT, SPINA.GD, estimated.GD, estimated.GDTT, SPINA.sGD, estimated.sGD, estimated.TSHI, estimated.sTSHI, estimated.TTSI
SPINA documentation built on May 2, 2019, 3:41 p.m.
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Description Usage Arguments Details Value Note Author(s) References See Also
Description
Calculate total step-up deiodinase activity (SPINA-GD) from equilibrium total hormone concentrations. This is an alias for estimated.GDTT.
Usage
1 | SPINA.GDTT(T4, T3)
|
Arguments
T4 |
Total thyroxine (TT4) concentration in nmol/L. |
T3 |
Total triiodothyronine (TT3) concentation in pmol/L |
Details
This function is able to do vectorised calculations.
Value
This function returns step-up deiodinase activity as a numeric result representing a single value or a vector, depending on the vector length of the arguments. Results are in nmol/s.
Note
The software functions described in this document are intended for research use only. Hormone levels should have been obtained simultaneously in order to avoid bias by transition effects.
Author(s)
Johannes W. Dietrich
References
Dietrich J. W., Landgrafe G., Fotiadou E. H. 2012 TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis. J Thyroid Res. 2012;2012:351864. doi: 10.1155/2012/351864. PMID: 23365787; PMCID: PMC3544290.
Dietrich J. W., Landgrafe-Mende G., Wiora E., Chatzitomaris A., Klein H. H., Midgley J. E., Hoermann R. 2016 Calculated Parameters of Thyroid Homeostasis: Emerging Tools for Differential Diagnosis and Clinical Research. Front Endocrinol (Lausanne). 2016 Jun 9;7:57. doi: 10.3389/fendo.2016.00057. PMID: 27375554; PMCID: PMC4899439.
See Also
SPINA.GT, estimated.GT, SPINA.GTT, estimated.GTT, SPINA.GD, estimated.GD, estimated.GDTT, SPINA.sGD, estimated.sGD, estimated.TSHI, estimated.sTSHI, estimated.TTSI
R Package Documentation
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We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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