estimated.GDTT: Calculated Sum Activity of Step-Up Deiodinases (SPINA-GD)

Description Usage Arguments Details Value Note Author(s) References See Also

Description

Calculate total step-up deiodinase activity (SPINA-GD) from equilibrium total hormone concentrations.

Usage

1

Arguments

T4

Total thyroxine (TT4) concentration in nmol/L.

T3

Total triiodothyronine (TT3) concentation in pmol/L

Details

This function is able to do vectorised calculations.

Value

This function returns step-up deiodinase activity as a numeric result representing a single value or a vector, depending on the vector length of the arguments. Results are in nmol/s.

Note

The software functions described in this document are intended for research use only. Hormone levels should have been obtained simultaneously in order to avoid bias by transition effects.

Author(s)

Johannes W. Dietrich

References

Dietrich J. W., Landgrafe G., Fotiadou E. H. 2012 TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis. J Thyroid Res. 2012;2012:351864. doi: 10.1155/2012/351864. PMID: 23365787; PMCID: PMC3544290.

Dietrich J. W., Landgrafe-Mende G., Wiora E., Chatzitomaris A., Klein H. H., Midgley J. E., Hoermann R. 2016 Calculated Parameters of Thyroid Homeostasis: Emerging Tools for Differential Diagnosis and Clinical Research. Front Endocrinol (Lausanne). 2016 Jun 9;7:57. doi: 10.3389/fendo.2016.00057. PMID: 27375554; PMCID: PMC4899439.

See Also

SPINA.GT, estimated.GT, SPINA.GTT, estimated.GTT, SPINA.GD, estimated.GD, SPINA.GDTT, SPINA.sGD, estimated.sGD, estimated.TSHI, estimated.sTSHI, estimated.TTSI


SPINA documentation built on May 2, 2019, 3:41 p.m.

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