study_peds: Example pedigrees

Description Usage Format References

Description

This data set contains ped data for five ascertiained pedigrees. The ascertained pedigrees were simulated by the sim_RVped function, which is included with the R package SimRVPedigree.

Usage

1

Format

A data frame with 77 rows and 15 variables:

FamID

Family identification number.

ID

Individual identification number.

sex

Sex identification variable: sex = 0 for males, and sex = 1 females.

dadID

Identification number of father

momID

Identification number of mother

affected

disease-affection status: affected = TRUE if individual has developed disease, and FALSE otherwise.

DA1

Paternally inherited allele at the familial disease locus: DA1 = 1 if the casual variant is inherited, and 0 otherwise.

DA2

Maternally inherited allele at the familial disease locus: DA2 = 1 if the casual variant is inherited, and 0 otherwise.

birthYr

The individual's birth year.

onsetYr

The individual's year of disease onset, when applicable, and NA otherwise.

deathYr

The individual's year of death, when applicable, and NA otherwise.

RR

The subject's relative-risk of disease

available

Availability status: available = TRUE if individual is recalled by the proband, and FALSE if not recalled or a marry-in.

Gen

The individual's generation number relative to the eldest pedigree founder. That is, the seed founder will have Gen = 1, his or her offspring will have Gen = 2, etc.

proband

Proband identification variable: proband = TRUE if the individual is the proband, and FALSE otherwise.

References

Christina Nieuwoudt and Jinko Graham (2018).SimRVPedigree:Simulate Pedigrees Ascertained for a Rare Disease.R package version 0.3.0.https://CRAN.R-project.org/package=SimRVPedigree.


SimRVSequences documentation built on July 1, 2020, 6:03 p.m.