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#' @title Example 3.9 from Generalized Linear Mixed Models: Modern Concepts, Methods and Applications by Walter W. Stroup(p-118)
#' @name Exam3.9
#' @description Exam3.9 used to differentiate conditional and marginal binomial models with and without interaction for S2 variable.
#' @author \enumerate{
#' \item Muhammad Yaseen (\email{myaseen208@@gmail.com})
#' \item Adeela Munawar (\email{adeela.uaf@@gmail.com})
#' }
#' @references \enumerate{
#' \item Stroup, W. W. (2012).
#' \emph{Generalized Linear Mixed Models: Modern Concepts, Methods and Applications}.
#' CRC Press.
#' }
#' @seealso
#' \code{\link{DataSet3.2}}
#'
#' @import parameters
#' @import emmeans
#' @importFrom MASS glmmPQL
#' @importFrom nlme lme
#'
#' @examples
#' #-----------------------------------------------------------------------------------
#' ## Binomial conditional GLMM without interaction, logit link
#' #-----------------------------------------------------------------------------------
#' library(MASS)
#' DataSet3.2$trt <- factor( x = DataSet3.2$trt )
#' DataSet3.2$loc <- factor( x = DataSet3.2$loc )
#'
#' Exam3.9.fm1 <-
#' glmmPQL(
#' fixed = S2/Nbin~trt
#' , random = ~1|loc
#' , family = quasibinomial(link = "logit")
#' , data = DataSet3.2
#' , niter = 10
#' , verbose = TRUE
#' )
#' summary(Exam3.9.fm1)
#' library(parameters)
#' model_parameters(Exam3.9.fm1)
#'
#' #-------------------------------------------------------------
#' ## treatment means
#' #-------------------------------------------------------------
#' library(emmeans)
#' emmeans(object = Exam3.9.fm1, specs = ~trt, type = "response")
#' emmeans(object = Exam3.9.fm1, specs = ~trt, type = "link")
#' emmeans(object = Exam3.9.fm1, specs = ~trt, type = "logit")
#'
#' ##--- Normal Approximation
#' library(nlme)
#' Exam3.9fm2 <-
#' lme(
#' fixed = S2/Nbin~trt
#' , data = DataSet3.2
#' , random = ~1|loc
#' , method = c("REML", "ML")[1]
#' )
#'
#' Exam3.9fm2
#' model_parameters(Exam3.9fm2)
#'
#' emmeans(object = Exam3.9fm2, specs = ~trt)
#'
#'
#' ##---Binomial GLMM with interaction
#' Exam3.9fm3 <-
#' glmmPQL(
#' fixed = S2/Nbin~trt
#' , random = ~1|trt/loc
#' , family = quasibinomial(link = "logit")
#' , data = DataSet3.2
#' , niter = 10
#' , verbose = TRUE
#' )
#' summary(Exam3.9fm3)
#' model_parameters(Exam3.9fm3)
#' emmeans(object = Exam3.9fm3, specs = ~trt)
#'
#'
#' ##---Binomial Marginal GLMM(assuming compound symmetry)
#' Exam3.9fm4 <-
#' glmmPQL(
#' fixed = S2/Nbin~trt
#' , random = ~1|loc
#' , family = quasibinomial(link = "logit")
#' , data = DataSet3.2
#' , correlation = corCompSymm(form = ~1|loc)
#' , niter = 10
#' , verbose = TRUE
#' )
#' summary(Exam3.9fm4)
#' model_parameters(Exam3.9fm4)
#' emmeans(object = Exam3.9fm4, specs = ~trt)
#'
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