estimate_mutual_information_SurvSurv: Estimate the Mutual Information in the Survival-Survival...

In Surrogate: Evaluation of Surrogate Endpoints in Clinical Trials

Estimate the Mutual Information in the Survival-Survival Setting

Description

estimate_mutual_information_SurvSurv() estimates the mutual information for a sample of individual causal treatment effects with a time-to-event surrogate and a time-to-event true endpoint. The mutual information is estimated by first estimating the bivariate density and then computing the mutual information for the estimated density.

Usage

estimate_mutual_information_SurvSurv(delta_S, delta_T, minfo_prec)

Arguments

delta_S	(numeric) Vector of individual causal treatment effects on the surrogate.
delta_T	(numeric) Vector of individual causal treatment effects on the true endpoint.
minfo_prec	Number of quasi Monte-Carlo samples for the numerical integration to obtain the mutual information. If this value is 0 (default), the mutual information is not computed and NA is returned for the mutual information and derived quantities.

Value

(numeric) estimated mutual information.

Surrogate documentation built on Sept. 25, 2023, 5:07 p.m.