Man pages for Surrogate
Evaluation of Surrogate Endpoints in Clinical Trials

AA.MultSCompute the multiple-surrogate adjusted association
ARMDData of the Age-Related Macular Degeneration Study
ARMD.MultSData of the Age-Related Macular Degeneration Study with...
BifixedContContFits a bivariate fixed-effects model to assess surrogacy in...
BimixedContContFits a bivariate mixed-effects model to assess surrogacy in...
Bootstrap.MEP.BinBinBootstrap 95% CI around the maximum-entropy ICA and SPF...
CausalDiagramBinBinDraws a causal diagram depicting the median informational...
CausalDiagramContContDraws a causal diagram depicting the median correlations...
CIGTSData of the Collaborative Initial Glaucoma Treatment Study
CIGTS_BinContData of the Collaborative Initial Glaucoma Treatment Study...
comb27.BinBinAssesses the surrogate predictive value of each of the 27...
ECTApply the Entropy Concentration Theorem
Fano.BinBinEvaluate the possibility of finding a good surrogate in the...
FixedBinBinITFits (univariate) fixed-effect models to assess surrogacy in...
FixedBinContITFits (univariate) fixed-effect models to assess surrogacy in...
FixedContBinITFits (univariate) fixed-effect models to assess surrogacy in...
FixedContContITFits (univariate) fixed-effect models to assess surrogacy in...
FixedDiscrDiscrITInvestigates surrogacy for binary or ordinal outcomes using...
ICABinBinAssess surrogacy in the causal-inference single-trial setting...
ICABinBinCounterAssumICA (binary-binary setting) that is obtaied when the...
ICA.BinBin.Grid.FullAssess surrogacy in the causal-inference single-trial setting...
ICA.BinBin.Grid.SampleAssess surrogacy in the causal-inference single-trial setting...
ICA.BinBin.Grid.Sample.UncertAssess surrogacy in the causal-inference single-trial setting...
ICABinContAssess surrogacy in the causal-inference single-trial setting...
ICAContContAssess surrogacy in the causal-inference single-trial setting...
ICA.ContCont.Mult_altAssess surrogacy in the causal-inference single-trial setting...
ICA.ContCont.MultSAssess surrogacy in the causal-inference single-trial setting...
ICA.Sample.ContContAssess surrogacy in the causal-inference single-trial setting...
LongToWideReshapes a dataset from the 'long' format (i.e., multiple...
MarginalProbsComputes marginal probabilities for a dataset where the...
MaxEntICABinBinUse the maximum-entropy approach to compute ICA in the...
MaxEntICAContContUse the maximum-entropy approach to compute ICA in the...
MaxEntSPFBinBinUse the maximum-entropy approach to compute SPF (surrogate...
MICAContContAssess surrogacy in the causal-inference multiple-trial...
MICA.Sample.ContContAssess surrogacy in the causal-inference multiple-trial...
MinSurrContContExamine the plausibility of finding a good surrogate endpoint...
MixedContContITFits (univariate) mixed-effect models to assess surrogacy in...
OvarianThe Ovarian dataset
plot.CausalInferencePlots the (Meta-Analytic) Individual Causal Association when...
plot.comb27.BinBinPlots the distribution of prediction error functions in...
plot.Fano.BinBinPlots the distribution of R^2_{HL} either as a density or as...
Plot.FixedDiscrDiscrITProvides plots of trial-level surrogacy in the...
plot.ICABinBinPlots the (Meta-Analytic) Individual Causal Association and...
plot.ICABinContPlots the (Meta-Analytic) Individual Causal Association and...
plot.ICA.ContCont.MultPlots the Individual Causal Association in the setting where...
plot.InformationTheoreticProvides plots of trial- and individual-level surrogacy in...
plot.InformationTheoreticBinCombnProvides plots of trial- and individual-level surrogacy in...
plot.InformationTheoreticSurvSurvProvides plots of trial- and individual-level surrogacy in...
plot.MaxEntContContPlots the sensitivity-based and maximum entropy based...
plot.MaxEntICABinBinPlots the sensitivity-based and maximum entropy based...
plot.MaxEntSPFBinBinPlots the sensitivity-based and maximum entropy based...
plot.MetaAnalyticProvides plots of trial- and individual-level surrogacy in...
plot.MinSurrContContGraphically illustrates the theoretical plausibility of...
plot.PPE.BinBinPlots the distribution of either PPE, RPE or R^2_{H} either...
Plot.PredTrialTContContPlots the expected treatment effect on the true endpoint in a...
plot.SPPBinBinPlots the surrogate predictive function (SPF) in the...
plot.SPPBinContPlots the surrogate predictive function (SPF) in the...
plot.TrialLevelITProvides a plots of trial-level surrogacy in the...
plot.TrialLevelMAProvides a plots of trial-level surrogacy in the...
plot.TwoStageSurvSurvPlots trial-level surrogacy in the meta-analytic framework...
Pos.Def.MatricesGenerate 4 by 4 correlation matrices and flag the positive...
PPE.BinBinEvaluate a surrogate predictive value based on the minimum...
Pred.TrialT.ContContCompute the expected treatment effect on the true endpoint in...
PrenticeEvaluates surrogacy based on the Prentice criteria for...
RandVecGenerate random vectors with a fixed sum
Restrictions.BinBinExamine restrictions in pi_{f} under different montonicity...
SchizoData of five clinical trials in schizophrenia
Schizo_BinData of a clinical trial in Schizophrenia (with binary...
Schizo_BinContData of a clinical trial in schizophrenia, with binary and...
Schizo_PANSSLongitudinal PANSS data of five clinical trials in...
Sim.Data.CounterfactualsSimulate a dataset that contains counterfactuals
Sim.Data.CounterfactualsBinBinSimulate a dataset that contains counterfactuals for binary...
Sim.Data.MTSSimulates a dataset that can be used to assess surrogacy in...
Sim.Data.STSSimulates a dataset that can be used to assess surrogacy in...
Sim.Data.STSBinBinSimulates a dataset that can be used to assess surrogacy in...
Single.Trial.RE.AAConducts a surrogacy analysis based on the single-trial...
SPP.BinBinEvaluate the surrogate predictive function (SPF) in the...
SPP.BinContEvaluate the surrogate predictive function (SPF) in the...
summary.genSummary
SurvSurvAssess surrogacy for two survival endpoints based on...
Test.MonoTest whether the data are compatible with monotonicity for S...
TrialLevelITEstimates trial-level surrogacy in the information-theoretic...
TrialLevelMAEstimates trial-level surrogacy in the meta-analytic...
TwoStageSurvSurvAssess trial-level surrogacy for two survival endpoints using...
UnifixedContContFits univariate fixed-effect models to assess surrogacy in...
UnimixedContContFits univariate mixed-effect models to assess surrogacy in...
Surrogate documentation built on April 21, 2018, 1:03 a.m.