Man pages for Surrogate
Evaluation of Surrogate Endpoints in Clinical Trials

AA.MultSCompute the multiple-surrogate adjusted association
ARMDData of the Age-Related Macular Degeneration Study
ARMD.MultSData of the Age-Related Macular Degeneration Study with...
BifixedContContFits a bivariate fixed-effects model to assess surrogacy in...
BimixedContContFits a bivariate mixed-effects model to assess surrogacy in...
CausalDiagramBinBinDraws a causal diagram depicting the median informational...
CausalDiagramContContDraws a causal diagram depicting the median correlations...
CIGTSData of the Collaborative Initial Glaucoma Treatment Study
CIGTS_BinContData of the Collaborative Initial Glaucoma Treatment Study...
comb27.BinBinAssesses the surrogate predictive value of each of the 27...
ECTApply the Entropy Concentration Theorem
Fano.BinBinEvaluate the possibility of finding a good surrogate in the...
FixedBinBinITFits (univariate) fixed-effect models to assess surrogacy in...
FixedBinContITFits (univariate) fixed-effect models to assess surrogacy in...
FixedContBinITFits (univariate) fixed-effect models to assess surrogacy in...
FixedContContITFits (univariate) fixed-effect models to assess surrogacy in...
FixedDiscrDiscrITInvestigates surrogacy for binary or ordinal outcomes using...
ICABinBinAssess surrogacy in the causal-inference single-trial setting...
ICABinBinCounterAssumICA (binary-binary setting) that is obtaied when the...
ICA.BinBin.Grid.FullAssess surrogacy in the causal-inference single-trial setting...
ICA.BinBin.Grid.SampleAssess surrogacy in the causal-inference single-trial setting...
ICA.BinBin.Grid.Sample.UncertAssess surrogacy in the causal-inference single-trial setting...
ICABinContAssess surrogacy in the causal-inference single-trial setting...
ICAContContAssess surrogacy in the causal-inference single-trial setting...
ICA.ContCont.Mult_altAssess surrogacy in the causal-inference single-trial setting...
ICA.ContCont.MultSAssess surrogacy in the causal-inference single-trial setting...
ICA.Sample.ContContAssess surrogacy in the causal-inference single-trial setting...
LongToWideReshapes a dataset from the 'long' format (i.e., multiple...
MarginalProbsComputes marginal probabilities for a dataset where the...
MaxEntICABinBinUse the maximum-entropy approach to compute ICA in the...
MaxEntICAContContUse the maximum-entropy approach to compute ICA in the...
MaxEntSPFBinBinUse the maximum-entropy approach to compute SPF (surrogate...
MICAContContAssess surrogacy in the causal-inference multiple-trial...
MICA.Sample.ContContAssess surrogacy in the causal-inference multiple-trial...
MinSurrContContExamine the plausibility of finding a good surrogate endpoint...
MixedContContITFits (univariate) mixed-effect models to assess surrogacy in...
OvarianThe Ovarian dataset
plot.CausalInferencePlots the (Meta-Analytic) Individual Causal Association when...
plot.comb27.BinBinPlots the distribution of prediction error functions in...
plot.Fano.BinBinPlots the distribution of R^2_{HL} either as a density or as...
Plot.FixedDiscrDiscrITProvides plots of trial-level surrogacy in the...
plot.ICABinBinPlots the (Meta-Analytic) Individual Causal Association and...
plot.ICABinContPlots the (Meta-Analytic) Individual Causal Association and...
plot.ICA.ContCont.MultPlots the Individual Causal Association in the setting where...
plot.InformationTheoreticProvides plots of trial- and individual-level surrogacy in...
plot.InformationTheoreticBinCombnProvides plots of trial- and individual-level surrogacy in...
plot.InformationTheoreticSurvSurvProvides plots of trial- and individual-level surrogacy in...
plot.MaxEntContContPlots the sensitivity-based and maximum entropy based...
plot.MaxEntICABinBinPlots the sensitivity-based and maximum entropy based...
plot.MaxEntSPFBinBinPlots the sensitivity-based and maximum entropy based...
plot.MetaAnalyticProvides plots of trial- and individual-level surrogacy in...
plot.MinSurrContContGraphically illustrates the theoretical plausibility of...
plot.PPE.BinBinPlots the distribution of either PPE, RPE or R^2_{H} either...
Plot.PredTrialTContContPlots the expected treatment effect on the true endpoint in a...
plot.SPPBinBinPlots the surrogate predictive function (SPF).
plot.TrialLevelITProvides a plots of trial-level surrogacy in the...
plot.TrialLevelMAProvides a plots of trial-level surrogacy in the...
plot.TwoStageSurvSurvPlots trial-level surrogacy in the meta-analytic framework...
Pos.Def.MatricesGenerate 4 by 4 correlation matrices and flag the positive...
PPE.BinBinEvaluate a surrogate predictive value based on the minimum...
Pred.TrialT.ContContCompute the expected treatment effect on the true endpoint in...
PrenticeEvaluates surrogacy based on the Prentice criteria for...
RandVecGenerate random vectors with a fixed sum
Restrictions.BinBinExamine restrictions in pi_{f} under different montonicity...
SchizoData of five clinical trials in schizophrenia
Schizo_BinData of a clinical trial in Schizophrenia (with binary...
Schizo_BinContData of a clinical trial in schizophrenia, with binary and...
Schizo_PANSSLongitudinal PANSS data of five clinical trials in...
Sim.Data.CounterfactualsSimulate a dataset that contains counterfactuals
Sim.Data.CounterfactualsBinBinSimulate a dataset that contains counterfactuals for binary...
Sim.Data.MTSSimulates a dataset that can be used to assess surrogacy in...
Sim.Data.STSSimulates a dataset that can be used to assess surrogacy in...
Sim.Data.STSBinBinSimulates a dataset that can be used to assess surrogacy in...
Single.Trial.RE.AAConducts a surrogacy analysis based on the single-trial...
SPP.BinBinEvaluate the surrogate predictive function (SPF) in the...
summary.genSummary
SurvSurvAssess surrogacy for two survival endpoints based on...
Test.MonoTest whether the data are compatible with monotonicity for S...
TrialLevelITEstimates trial-level surrogacy in the information-theoretic...
TrialLevelMAEstimates trial-level surrogacy in the meta-analytic...
TwoStageSurvSurvAssess trial-level surrogacy for two survival endpoints using...
UnifixedContContFits univariate fixed-effect models to assess surrogacy in...
UnimixedContContFits univariate mixed-effect models to assess surrogacy in...
Surrogate documentation built on Oct. 9, 2017, 1:03 a.m.