Schizo: Data of five clinical trials in schizophrenia
In Surrogate: Evaluation of Surrogate Endpoints in Clinical Trials
Schizo R Documentation
Data of five clinical trials in schizophrenia
Description
These are the data of five clinical trials in schizophrenia. A total of 2128 patients were treated by 198 investiagators (psychiatrists). Patients' schizophrenic symptoms were measured using the PANSS, BPRS, and CGI. There were two treatment conditions (risperidone and control).
Usage
data(Schizo)
Format
A data.frame with 2128 observations on 9 variables.
IdThe patient ID.
InvestIDThe ID of the investigator (psychiatrist) who treated the patient.
TreatThe treatment indicator, coded as -1 = control and 1 = Risperidone.
CGIThe change in the CGI score (= score at the start of the treatment - score at the end of the treatment).
PANSSThe change in the PANSS score.
BPRSThe change in the PANSS score.
PANSS_BinThe dichotomized PANSS change score, coded as 1 = a reduction of
20% or more in the PANSS score (score at the end of the treatment relative to score at the beginning of the treatment), 0 = otherwise.
BPRS_BinThe dichotomized BPRS change score, coded as 1 = a reduction of 20% or more in the BPRS score (score at the end of the treatment relative to score at the beginning of the treatment), 0 = otherwise.
CGI_BinThe sichtomized change in the CGI score, coded as 1 = a change of more than 3 points on the original scale (score at the end of the treatment relative to score at the beginning of the treatment), 0 = otherwise.
Surrogate documentation built on Sept. 25, 2023, 5:07 p.m.
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| Schizo | R Documentation |
Data of five clinical trials in schizophrenia
Description
These are the data of five clinical trials in schizophrenia. A total of 2128 patients were treated by 198 investiagators (psychiatrists). Patients' schizophrenic symptoms were measured using the PANSS, BPRS, and CGI. There were two treatment conditions (risperidone and control).
Usage
data(Schizo)Format
A data.frame with 2128 observations on 9 variables.
IdThe patient ID.
InvestIDThe ID of the investigator (psychiatrist) who treated the patient.
TreatThe treatment indicator, coded as
-1= control and1= Risperidone.CGIThe change in the CGI score (= score at the start of the treatment - score at the end of the treatment).
PANSSThe change in the PANSS score.
BPRSThe change in the PANSS score.
PANSS_BinThe dichotomized PANSS change score, coded as
1= a reduction of 20% or more in the PANSS score (score at the end of the treatment relative to score at the beginning of the treatment),0= otherwise.BPRS_BinThe dichotomized BPRS change score, coded as
1= a reduction of 20% or more in the BPRS score (score at the end of the treatment relative to score at the beginning of the treatment),0= otherwise.CGI_BinThe sichtomized change in the CGI score, coded as
1= a change of more than3points on the original scale (score at the end of the treatment relative to score at the beginning of the treatment),0= otherwise.
R Package Documentation
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We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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