TER.deesc.1.B: Find the bootstrap distribution

In TERAplusB: Test for A+B Traditional Escalation Rule

Description

TER.deesc.1.B finds all possible combinations of 1+B design with specific dose-toxicity relations.

Usage

 TER.deesc.1.B(Dose,Prob.Dose,B,C,D,E)

Arguments

Dose	Dose levels
Prob.Dose	True Probability of toxicity
B	Number of added patients
C	Cutoff point 1
D	Cutoff point 2
E	Cutoff point 3

Value

tot.list	All possible combinations of 1+B design
Prob.result	Expected distribution of MTD
E.toxrate	Expected toxicity rate
E.n	Expected number of patients
E.time	Expected number of periods

References

Adaptive Design Methods in Clinical Trials - Chow and Chung

Examples

     library(TERAplusB)
     TER.deesc.1.B(c("D1","D2"),c(0.2,0.7),B=3,C=1,D=1,E=2)

TERAplusB documentation built on May 1, 2019, 9:19 p.m.