remove_rarevariants: A function used in spmle and acoarm to remove rare-variant...

In TwoPhaseInd: Estimate Gene-Treatment Interaction Exploiting Randomization

A function used in spmle and acoarm to remove rare-variant covariates

Description

It is used to remove rare-variant covariates, which can cause divergence problem.

Usage

remove_rarevariants(data, cutoff = 0.02)

Arguments

data	A dataframe composed of covariates.
cutoff	Proportion cutoff. If data composed of more than (1-cutoff) proportion of a constant value, we call it rare-variant.

Details

The function removes rare-variant covariates.

Value

A logical vector composed of True or False. True means a covariate is rare-variant.

Author(s)

James Y. Dai

Examples

## Load the example data
data(acodata)
result <- remove_rarevariants(acodata[, c("vacc1_evinf","fcgr2a.3")])

TwoPhaseInd documentation built on March 18, 2022, 7:52 p.m.