VNM: Using V-algorithm and Newton-Raphson Method to Obtain Multiple-objective Optimal Design

Using V-algorithm and Newton-Raphson method to obtain multiple-objective optimal design for estimating the shape of dose-response, the ED50 (the dose producing an effect midway between the expected responses at the extreme doses) and the MED (the minimum effective dose level) for the 2,3,4-parameter logistic models and for evaluating its efficiencies for the three objectives.

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AuthorSeung Won Hyun, Weng Kee Wong, and Yarong Yang
Date of publication2016-02-11 00:39:22
MaintainerYarong Yang <>
LicenseGPL (>= 2)

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