Fit proportional hazards models with a weighted cumulative exposure, based on a weight function estimated from cubic regression b-splines. This implementation of WCE assumes that the dataset is in the interval format with one line per unit of time.
Maintainer: Marie-Pierre Sylvestre <[email protected]>
Sylvestre MP, Abrahamowicz M. Flexible modeling of the cumulative effects of time-dependent exposures on the hazard. Stat Med. 2009;28(27):3437-53. Abrahamowicz M, Beauchamp M-E, Sylvestre M-P. Comparison of alternative models for linking drug exposure with adverse effects. Stat Med. 2012;31(11-12):1014-1030.
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