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adoptr: Adaptive Optimal Two-Stage Designs
Optimize one or two-arm, two-stage designs for clinical trials with respect to several implemented objective criteria or custom objectives. Optimization under uncertainty and conditional (given stage-one outcome) constraints are supported. See Pilz et al. (2019) <doi:10.1002/sim.8291> and Kunzmann et al. (2021) <doi:10.18637/jss.v098.i09> for details.
Package details |
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| Author | Kevin Kunzmann [aut, cph] (<https://orcid.org/0000-0002-1140-7143>), Maximilian Pilz [aut, cre] (<https://orcid.org/0000-0002-9685-1613>), Jan Meis [aut] (<https://orcid.org/0000-0001-5407-7220>), Nico Bruder [aut] |
| Maintainer | Maximilian Pilz <maximilian.pilz@itwm.fraunhofer.de> |
| License | MIT + file LICENSE |
| Version | 1.0.1 |
| URL | https://github.com/optad/adoptr https://optad.github.io/adoptr/ |
| Package repository | View on CRAN |
| Installation |
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