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Optimize one or two-arm, two-stage designs for clinical trials with respect to several pre-implemented objective criteria or implement custom objectives. Optimization under uncertainty and conditional (given stage-one outcome) constraints are supported. See <doi:10.1002/sim.8291> and <doi:10.18637/jss.v098.i09> for details.
Package details |
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Author | Kevin Kunzmann [aut, cre] (<https://orcid.org/0000-0002-1140-7143>), Maximilian Pilz [aut] (<https://orcid.org/0000-0002-9685-1613>) |
Maintainer | Kevin Kunzmann <kevin.kunzmann@mrc-bsu.cam.ac.uk> |
License | MIT + file LICENSE |
Version | 1.0.0 |
URL | https://github.com/kkmann/adoptr |
Package repository | View on CRAN |
Installation |
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