adoptr: Adaptive Optimal Two-Stage Designs

Optimize one or two-arm, two-stage designs for clinical trials with respect to several implemented objective criteria or custom objectives. Optimization under uncertainty and conditional (given stage-one outcome) constraints are supported. See Pilz et al. (2019) <doi:10.1002/sim.8291> and Kunzmann et al. (2021) <doi:10.18637/jss.v098.i09> for details.

Package details

AuthorKevin Kunzmann [aut, cph] (<>), Maximilian Pilz [aut, cre] (<>), Jan Meis [aut] (<>), Nico Bruder [aut]
MaintainerMaximilian Pilz <>
LicenseMIT + file LICENSE
Package repositoryView on CRAN
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adoptr documentation built on June 22, 2024, 9:21 a.m.