annovarR: Integrated Framework to Annotate Genetic Variants

The 'annovarR' package provides R functions as well as database resources which offer an integrated framework to annotate genetic variants from genome and transcriptome data. The wrapper functions of 'annovarR' unified the interface of many published annotation tools, such as 'VEP' (<http://asia.ensembl.org/info/docs/tools/vep/index.html>), 'ANNOVAR' (<http://annovar.openbioinformatics.org/>), 'vcfanno' (<https://github.com/brentp/vcfanno>) and 'AnnotationDbi' (<http://www.bioconductor.org/packages/release/bioc/html/AnnotationDbi.html>). It also simplified the use of some of the external annotation tools in R. Besides, massive published genetic variants annotation databases were integrated into 'annovarR'. For example, 'annovarR' provides a newly RNA-seq allele frequency database, BRVar, which built from total 1,285 cases public B-progenitor acute lymphoblastic leukemia (B-ALL) transcriptome data.

Package details

AuthorJianfeng Li [aut, cre]
MaintainerJianfeng Li <[email protected]>
LicenseMIT + file LICENSE
Version1.0.0
URL https://github.com/JhuangLab/annovarR
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("annovarR")

Try the annovarR package in your browser

Any scripts or data that you put into this service are public.

annovarR documentation built on Jan. 9, 2018, 5:05 p.m.