pk_1cmt_inf_dose_for_range: Calculate dose based on a given AUC24, Cmax, and Cmin,...

In clinPK: Clinical Pharmacokinetics Toolkit

Calculate dose based on a given AUC24, Cmax, and Cmin, assuming 1-compartment model

Description

Calculate dose based on a given AUC24, Cmax, and Cmin, assuming 1-compartment model

Usage

pk_1cmt_inf_dose_for_range(
  target = 500,
  type = "auc",
  conc_range = c(10, 40),
  parameters = list(),
  interval = 24,
  t_inf = 1,
  optimize_interval = TRUE,
  round_interval = TRUE
)

Arguments

target	numeric value of target
type	target type, one of 'auc', 'auc24', 'ctrough', 'cmin'
conc_range	concentration range to stay within, vector of length 2
parameters	list of 'CL' and 'V', or 'KEL' and 'CL'
interval	dosing interval
t_inf	infusion time
optimize_interval	find optimal interval (to stay within 'conc_range'?
round_interval	round interval to nearest nominal interval?

clinPK documentation built on May 9, 2022, 9:06 a.m.