pk_2cmt_bolus: Concentration predictions for 2-compartmental PK model,...

In clinPK: Clinical Pharmacokinetics Toolkit

Concentration predictions for 2-compartmental PK model, single or multiple bolus doses

Description

Concentration predictions for 2-compartmental PK model, single or multiple bolus doses

Usage

pk_2cmt_bolus(
  t = c(0:24),
  dose = 100,
  tau = 12,
  CL = 3,
  V = 30,
  Q = 2,
  V2 = 20,
  ruv = NULL
)

Arguments

t	vector of time
dose	dose
tau	dosing interval
CL	clearance
V	volume of central compartment
Q	inter-compartimental clearance
V2	volume of peripheral compartment
ruv	residual error (list)

Examples

pk_2cmt_bolus(dose = 1000, tau = 24, CL = 5, V = 50, Q = 15, V2 = 200)

clinPK documentation built on May 29, 2024, 3:50 a.m.