View source: R/pk_2cmt_bolus_dose_from_cmax.R
pk_2cmt_bolus_dose_from_cmax | R Documentation |
Calculate dose to achieve steady state Cmax for 2-compartmental PK model bolus dosing at steady state
pk_2cmt_bolus_dose_from_cmax( cmax = 1, tau = 12, CL = 3, V = 30, Q = 2, V2 = 20 )
cmax |
desired trough concentration |
tau |
dosing interval |
CL |
clearance |
V |
volume of distribution |
Q |
inter-compartimental clearance |
V2 |
volume of peripheral compartment |
dos <- pk_2cmt_bolus_dose_from_cmax( cmax = 10, tau = 12, CL = 5, V = 50, Q = 20, V2 = 200) find_nearest_dose(dos, 100)
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