pk_2cmt_bolus_dose_from_cmax: Calculate dose to achieve steady state Cmax for...

Description Usage Arguments Examples

View source: R/pk_2cmt_bolus_dose_from_cmax.R

Description

Calculate dose to achieve steady state Cmax for 2-compartmental PK model bolus dosing at steady state

Usage

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pk_2cmt_bolus_dose_from_cmax(cmax = 1, tau = 12, CL = 3, V = 30,
  Q = 2, V2 = 20)

Arguments

cmax

desired trough concentration

tau

dosing interval

CL

clearance

V

volume of distribution

Q

inter-compartimental clearance

V2

volume of peripheral compartment

Examples

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dos <- pk_2cmt_bolus_dose_from_cmax(
  cmax = 10, tau = 12,
  CL = 5, V = 50, Q = 20, V2 = 200)
find_nearest_dose(dos, 100)

clinPK documentation built on May 2, 2019, 9:04 a.m.