pk_2cmt_inf_dose_from_cmin: Calculate dose to achieve steady state trough for...

Description Usage Arguments Examples

View source: R/pk_2cmt_inf_dose_from_cmin.R

Description

Calculate dose to achieve steady state trough for 2-compartmental PK model with infusion dosing at steady state

Usage

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pk_2cmt_inf_dose_from_cmin(cmin = 1, tau = 12, t_inf = 1, CL = 3,
  V = 30, Q = 2, V2 = 20)

Arguments

cmin

desired trough concentration

tau

dosing interval

t_inf

infusion time

CL

clearance

V

volume of distribution

Q

inter-compartimental clearance

V2

volume of peripheral compartment

Examples

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dos <- pk_2cmt_inf_dose_from_cmin(
  cmin = 10, tau = 12, t_inf = 2,
  CL = 5, V = 50, Q = 20, V2 = 200)
find_nearest_dose(dos, 100)

clinPK documentation built on May 2, 2019, 9:04 a.m.