pk_2cmt_inf_ss: Concentration predictions for 2-compartmental PK model with...

In clinPK: Clinical Pharmacokinetics Toolkit

Concentration predictions for 2-compartmental PK model with infusion dosing at steady state

Description

Concentration predictions for 2-compartmental PK model with infusion dosing at steady state

Usage

pk_2cmt_inf_ss(
  t = c(0:24),
  dose = 100,
  t_inf = 1,
  tau = 12,
  CL = 3,
  V = 30,
  Q = 2,
  V2 = 20,
  ruv = NULL
)

Arguments

t	vector of time
dose	dose
t_inf	infusion time
tau	dosing interval
CL	clearance
V	volume of distribution
Q	inter-compartimental clearance
V2	volume of peripheral compartment
ruv	residual variability, specified as list with optional arguments for proportional, additive, or exponential components, e.g. 'list(prop=0.1, add=1, exp=0)'

Examples

pk_2cmt_inf_ss(
  dose = 1000, tau = 12, t_inf = 2,
  CL = 5, V = 50, Q = 20, V2 = 200)

clinPK documentation built on May 29, 2024, 3:50 a.m.