Description Usage Arguments Details Value Author(s) References See Also Examples
Estimation of gene-environment interaction on the additive scale for case-control data
1 | gxe.cc(cases, contr, pD)
|
cases |
a vector containing numbers of cases observed in the gene environment groups <G=0,E=0>, <G=1,E=0>, <G=0,E=1> and <G=1,E=1> |
contr |
a vector containing numbers of controls observed in the gene environment groups <G=0,E=0>, <G=1,E=0>, <G=0,E=1> and <G=1,E=1> |
pD |
disease prevalence should be either less than 1 (for a known value) or a vector of observed numbers of affected and unaffected individuals from an external data set |
see Nguyen et al. 2013
GxE.cc |
a list containing the interaction estimate, the corresponding variance and the boundaries of the 95% of the confidence interval |
Thuy Trang Nguyen
Making Medical Decisions in Dependence of Genetic Background: Estimation of the Utility of DNA Testing in Clinical, Pharmaco-Epidemiological or Genetic Studies. Nguyen TT, Schaefer H, Timmesfeld N. Genet Epidemiol. 2013 Apr 4. doi: 10.1002/gepi.21701
gxe.coh
, utility.coh
, utility.cc
1 2 3 4 5 6 7 |
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