ocarcinoma: Ovarian Carcinoma

In coin: Conditional Inference Procedures in a Permutation Test Framework

Ovarian Carcinoma

Description

Survival times of 35 women suffering from ovarian carcinoma at stadium II and IIA.

Usage

ocarcinoma

Format

A data frame with 35 observations on 3 variables.

time

time (days).

stadium

a factor with levels "II" and "IIA".

event

status indicator for time: FALSE for right-censored observations and TRUE otherwise.

Details

Data from Fleming et al. (1980) and Fleming, Green and Harrington (1984). Reanalysed in Schumacher and Schulgen (2002).

Source

Fleming, T. R., Green, S. J. and Harrington, D. P. (1984). Considerations for monitoring and evaluating treatment effects in clinical trials. Controlled Clinical Trials 5(1), 55–66. \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1016/0197-2456(84)90150-8")}

Fleming, T. R., O'Fallon, J. R., O'Brien, P. C. and Harrington, D. P. (1980). Modified Kolmogorov-Smirnov test procedures with application to arbitrarily right-censored data. Biometrics 36(4), 607–625. \Sexpr[results=rd]{tools:::Rd_expr_doi("10.2307/2556114")}

References

Schumacher, M. and Schulgen, G. (2002). Methodik Klinischer Studien: Methodische Grundlagen der Planung, Durchführung und Auswertung. Heidelberg: Springer.

Examples

## Exact logrank test
lt <- logrank_test(Surv(time, event) ~ stadium, data = ocarcinoma,
                   distribution = "exact")

## Test statistic
statistic(lt)

## P-value
pvalue(lt)

coin documentation built on Sept. 27, 2023, 5:09 p.m.