myeloma: Survival of multiple myeloma patients

In collett: Datasets from "Modelling Survival Data in Medical Research" by Collett

Survival of multiple myeloma patients

Description

Patients diagnosed with multiple myeloma who were diagnosed and treated with alkylating agents at West Virginia University Medical Center for ages 50-80 years.

Usage

myeloma

Format

A data frame with 48 rows and 10 variables:

patient

integer for a patient identifier

time

integer survival time in months

status

integer for status at follow-up (0=Alive, 1=Dead)

age

integer age at diagnosis in years

sex

integer for sex of the patient (1=male, 2=female)

bun

integer level of blood urea nitrogen at diagnosis (unit assumed to be mg/dL based on the normal range for adults reported by https://en.wikipedia.org/wiki/Blood_urea_nitrogen)

ca

integer serum calcium at diagnosis in mg/dL

hb

double for serum hemoglobin level at diagnosis in g/dL (equivalently, grams per 100 mL)

pcells

integer percent of plasma cells in the bone marrow at diagnosis

protein

integer indicator for whether or not the Bence-Jones protein was present in the urine at diagnosis (0=absent, 1=present)

Details

Krall et al (1975) did not provide the units for all of these measurements. In their analyses, they used some data transformations: log(bun). Collett (2023) converted data from Krall et al (1975): BUN is reported by Krall and colleagues as X1=log(BUN), however the log base and unit is unclear; Krall and colleagues reported for 65 individuals, including those younger than 50 and older than 80.

References

Krall JM, Uthoff VA, Harley JB. A step-up procedure for selecting variables associated with survival. Biometrics. 1975 Mar 1:49-57. \Sexpr[results=rd]{tools:::Rd_expr_doi("10.2307/2529709")}

Examples

## To be completed.

collett documentation built on April 3, 2025, 5:53 p.m.