Nothing
cpt <-
function (Z, T, leaveout = 0, class.methods = "forest", metric = "probability",
ensemble.metric = "mean.prob", paired = FALSE, perm.N = 1000,
leaveout.N = 100, comb.methods = c(class.methods, "ensemble"),
comb.method = "fisher")
{
T = as.factor(T)
train.methods = gettrainmethods(class.methods)
test.methods = gettestmethods(class.methods)
if (is.character(metric))
metric = getmetric(metric)
if (is.character(ensemble.metric))
ensemble.metric = getensemble.metric(ensemble.metric)
if (is.character(comb.method))
comb.method = getcombmethod(comb.method)
if ((leaveout > 0) && (leaveout < 1))
leaveout = ceiling(min(table(T)) * leaveout)
teststat = rep(NA, length(class.methods))
nulldist = matrix(NA, perm.N, length(class.methods) + 1)
colnames(nulldist) = c(class.methods, "ensemble")
for (method.i in 1:length(class.methods)) {
teststat = getteststat(Z, T, leaveout, train.methods,
test.methods, metric, ensemble.metric, leaveout.N)
}
if (paired) {
T = as.numeric(T) - 1
for (i in 1:perm.N) {
newT = T
newT[T == 0] = rbinom(length(T)/2, 1, 0.5)
newT[T == 1] = 1 - newT[T == 0]
newT = as.factor(newT)
nulldist[i, ] = getteststat(Z, newT, leaveout, train.methods,
test.methods, metric, ensemble.metric, leaveout.N)
}
}
else {
for (i in 1:perm.N) {
T = T[sample(length(T))]
nulldist[i, ] = getteststat(Z, T, leaveout, train.methods,
test.methods, metric, ensemble.metric, leaveout.N)
}
}
pvals = rep(NA, ncol(nulldist))
names(pvals) = colnames(nulldist)
nullpvaldist = matrix(NA, perm.N, ncol(nulldist))
colnames(nullpvaldist) = names(pvals)
for (method.i in 1:ncol(nulldist)) {
pvals[method.i] = sum(nulldist[, method.i] >= teststat[method.i])/perm.N
nullpvaldist[, method.i] = 1 - (rank(nulldist[, method.i],
ties.method = "min") - 1)/perm.N
}
nullcombpvaldist = apply(nullpvaldist[, comb.methods, drop = FALSE],
1, comb.method)
pval = sum(nullcombpvaldist <= comb.method(pvals[comb.methods]))/perm.N
if (length(class.methods) == 1)
return(list(pval = pvals[1], teststat = teststat[1],
nulldist = nulldist[, 1], pvals = pvals[1]))
return(list(pval = pval, teststat = teststat, nulldist = nulldist,
pvals = pvals))
}
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