ComboSimulations-class: 'ComboSimulations'

In crmPack: Object-Oriented Implementation of Dose Escalation Designs

ComboSimulations

Description

This class captures trial simulations from two-drug combination designs (DesignCombo).

It is intentionally separate from Simulations because DataCombo is not a subclass of Data, and final recommendations are dose combinations.

Usage

ComboSimulations(
  data,
  doses,
  fit,
  stop_reasons,
  stop_report,
  additional_stats,
  seed
)

.DefaultComboSimulations()

Arguments

data	(list) see slot definition.
doses	(matrix) see slot definition.
fit	(list) see slot definition.
stop_reasons	(list) see slot definition.
stop_report	(matrix) see slot definition.
additional_stats	(list) see slot definition.
seed	(integer) see slot definition.

Slots

data

(list) produced DataCombo objects.

doses

(matrix) final recommended dose combinations; one row per simulation run and two columns (one per drug).

fit

(list) final fitted toxicity surfaces for each simulation run.

stop_reasons

(list) stopping reasons for each simulation run.

stop_report

(matrix) matrix of stopping rule outcomes.

additional_stats

(list) list of additional statistical summary values.

seed

(integer) random generator state before starting the simulation.

Note

Typically, end users will not use the .DefaultComboSimulations() function.

crmPack documentation built on July 5, 2026, 9:06 a.m.