plot-dosefinding-missing-method: The graphical representation of dose-finding results.

In dfpk: Bayesian Dose-Finding Designs using Pharmacokinetics (PK) for Phase I Clinical Trials

Description

A plot selection showing either the dose escalation allocation of the selected trial or the plot of the final posterior distributions of the probability of toxicity at each dose or the boxplot of the sampling distribution of the probability of toxicity at each dose in the end of the trial over the total number of trials.

Usage

## S4 method for signature 'dosefinding,missing'
plot(x, y = NA, TR = 1, ask = TRUE,
  CI = TRUE, ...)

Arguments

x	a "dosefinding" object.
y	the "y" argument is not used in the plot-method for "dosefinding" object.
TR	The number of the selected trial that user wants to plot; defaults to 1.
ask	Choose plot or not; defaults to TRUE.
CI	Indicate if the "dosefinding" object includes the 95% credible interval for the posterior dose response plot; defaults to TRUE.
...	other arguments to the plot.default function can be passed here.

Author(s)

Artemis Toumazi [e-mail], Moreno Ursino [e-mail], Sarah Zohar [e-mail]

References

Ursino, M., et al, (2017) Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations, Biometrical Journal, <doi:10.1002/bimj.201600084>.

Toumazi, A., et al, (2018) dfpk: An R-package for Bayesian dose-finding designs using pharmacokinetics (PK) for phase I clinical trials, Computer Methods and Programs in Biomedicine, <doi:10.1016/j.cmpb.2018.01.023>.

dfpk documentation built on May 2, 2019, 8:31 a.m.