plot-scen-missing-method: The graphical representation of the drug's concentration in...

In dfpk: Bayesian Dose-Finding Designs using Pharmacokinetics (PK) for Phase I Clinical Trials

Description

The graphical representation of the drug's concentration in the plasma at time t after the drug administration.

Usage

## S4 method for signature 'scen,missing'
plot(x, y = NA, col = rainbow(length(x@doses)),
  xlab = "Time (hours)", ylab = "Concentration (mg/L)",
  main = "Pharmacokinetics: Concentration vs Time", ...)

Arguments

x	a "scen" object or a list of the selected trial from a "scen" object.
y	the "y" argument is not used in the plot-method for "scen" object.
col	the color argument to the plot.default function.
xlab	the label of x-axis.
ylab	the label of y-axis.
main	the title of the graph.
...	other arguments to the plot.default function can be passed here.

Author(s)

Artemis Toumazi [e-mail], Moreno Ursino [e-mail], Sarah Zohar [e-mail]

References

Ursino, M., et al, (2017) Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations, Biometrical Journal, <doi:10.1002/bimj.201600084>.

Toumazi, A., et al, (2018) dfpk: An R-package for Bayesian dose-finding designs using pharmacokinetics (PK) for phase I clinical trials, Computer Methods and Programs in Biomedicine, <doi:10.1016/j.cmpb.2018.01.023>.

dfpk documentation built on May 2, 2019, 8:31 a.m.