The directPA-package is designed for analysing pathways in experiments with multiple perturbations. The combination effects of different treatments are tested by rotating polar coordinates in two-dimentional space when the experiment contains two perturbations and corresponding controls, or spherical coordinates in three-dimensional space when the experiment contains three perturbations and corresponding controls.
Pengyi Yang <firstname.lastname@example.org> & Ellis Patrick <email@example.com>
Pengyi Yang, Ellis Patrick, Shi-Xiong Tan, Daniel J. Fazakerley, James Burchfield, Christopher Gribben, Matthew J. Prior, David E. James, Yee Hwa Yang, Direction pathway analysis of large-scale proteomics data reveals novel features of the insulin action pathway, submitted.
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