rotate2d: Polar Coordinates Rotation
In directPA: Direction Analysis for Pathways and Kinases

Description Usage Arguments Value Examples

Rotate to the direction of interest in polar coordinates by degree (e.g. pi/4).

1	rotate2d(T, degree = 0)

`T`	a numeric matrix (normally z-score converted) with 2 columns. The rows are genes or phosphorylation sites and the columns are treatments vs control statistics.
`degree`	the direction to be tested for enrichment. Specified as degree from to the original direction.

A rotated matrix with respect to the direction of interest.

# load the phosphoproteomics dataset
data(HEK)

# convert statistics into z-scores
HEK.zscores <- apply(HEK, 2, function(x){qnorm(rank(x)/(nrow(HEK)+1))})

# Rotate the matrix by 1/2 pi (i.e. down-regulation, dow-regulation).
HEK.rotated <- rotate2d(HEK.zscores, degree = pi/2)