Description Usage Arguments Details Value Examples

For each pair of matched (orthologous) genes from an object of class mtchedOrtholog calculates the concordance / discordance score. The rationale is to formulate a metric allowing to compare heterologous data sets, e.g. data sets from different sources, technical platforms or even organisms.

1 | ```
disco.score(x)
``` |

`x` |
object of class matchedOrtholog |

*\textrm{disco.score} := |logFC_1|\cdot|logFC_2|\cdot(|log_{10}(p_1)| + |log_{10}(p_2)|) \cdot \textrm{sign}(logFC_1) \cdot \textrm{sign}(logFC_2)*

Where

*logFC_1*log fold change of the expression change of the gene from the first data set

*logFC_2*log fold change of the expression change of the gene from the second data set

*p1*differential regulation p-value for the gene from the first data set

*p2*differential regulation p-value for the gene from the second data set

A numerical vector of the disco scores

1 2 |

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