drc: Analysis of Dose-Response Curves

Analysis of dose-response data is made available through a suite of flexible and versatile model fitting and after-fitting functions.

Author
Christian Ritz <ritz@bioassay.dk>, Jens C. Strebig <streibig@bioassay.dk>
Date of publication
2016-08-30 01:33:38
Maintainer
Christian Ritz <ritz@bioassay.dk>
License
GPL-2 | file LICENCE
Version
3.0-1
URLs

View on CRAN

Man pages

acidiq
Acifluorfen and diquat tested on Lemna minor.
algae
Volume of algae as function of increasing concentrations of a...
anova.drc
ANOVA for dose-response model fits
AR
Asymptotic regression model
auxins
Effect of technical grade and commercially formulated auxin...
backfit
Calculation of backfit values from a fitted dose-response...
barley
Leaf length of barley
baro5
The modified baro5 function
BC
The Brain-Cousens hormesis models
boxcox.drc
Transform-both-sides Box-Cox transformation
braincousens
The Brain-Cousens hormesis models
bread.drc
Bread and meat for the sandwich
cedergreen
The Cedergreen-Ritz-Streibig model
chickweed
Germination of common chickweed (_Stellaria media_)
CIcompX
Calculation of combination index for binary mixtures
coef.drc
Extract Model Coefficients
comped
Comparison of effective dose values
compParm
Comparison of parameters
confint.drc
Confidence Intervals for model parameters
CRS.4a
The Cedergreen-Ritz-Streibig model
CRS.5a
Cedergreen-Ritz-Streibig dose-reponse model for describing...
daphnids
Daphnia test
decontaminants
Performance of decontaminants used in the culturing of a...
deguelin
Deguelin applied to chrysanthemum aphis
drm
Fitting dose-response models
drmc
Sets control arguments
earthworms
Earthworm toxicity test
EDcomp
Comparison of relative potencies between dose-response curves
ED.drc
Estimating effective doses
etmotc
Effect of erythromycin on mixed sewage microorganisms
EXD
Exponential decay model
finney71
Example from Finney (1971)
fitted.drc
Extract fitted values from model
fplogistic
Fractional polynomial-logistic dose-response models
gammadr
Gamma dose-response model
G.aparine
Herbicide applied to Galium aparine
gaussian
Normal and log-normal biphasic dose-response models
germination
Germination of three crops
getInitial
Showing starting values used
getMeanFunctions
Display available dose-response models
glymet
Glyphosate and metsulfuron-methyl tested on algae.
gompertz
Mean function for the Gompertz dose-response or growth curve
gompertzd
The derivative of the Gompertz function
hatvalues.drc
Model diagnostics for nonlinear dose-response models
heartrate
Heart rate baroreflexes for rabbits
H.virescens
Mortality of tobacco budworms
isobole
Creating isobolograms
lepidium
Dose-response profile of degradation of agrochemical using...
lettuce
Hormesis in lettuce plants
lin.test
Lack-of-fit test for the mean structure based on cumulated...
LL.2
The two-parameter log-logistic function
LL.3
The three-parameter log-logistic function
LL.4
The four-parameter log-logistic function
LL.5
The five-parameter log-logistic function
llogistic
The log-logistic function
lnormal
Log-normal dose-response model
logistic
The logistic model
logLik.drc
Extracting the log likelihood
maED
Estimation of ED values using model-averaging
MAX
Maximum mean response
M.bahia
Effect of an effluent on the growth of mysid shrimp
mecter
Mechlorprop and terbythylazine tested on Lemna minor
metals
Data from heavy metal mixture experiments
methionine
Weight gain for different methionine sources
mixture
Fitting binary mixture models
MM
Michaelis-Menten model
modelFit
Assessing the model fit
mr.test
Mizon-Richard test for dose-response models
mselect
Dose-response model selection
multi2
Multistage dose-response model with quadratic terms
nasturtium
Dose-response profile of degradation of agrochemical using...
NEC
Dose-response model for estimation of no effect concentration...
neill.test
Neill's lack-of-fit test for dose-response models
noEffect
Testing if there is a dose effect at all
O.mykiss
Test data from a 21 day fish test
plot.drc
Plotting fitted dose-response curves
P.promelas
Effect of sodium pentachlorophenate on growth of fathead...
PR
Expected or predicted response
predict.drc
Prediction
print.drc
Printing key features
print.summary.drc
Printing summary of non-linear model fits
rdrm
Simulating a dose-response curve
residuals.drc
Extracting residuals from the fitted dose-response model
RScompetition
Competition between two biotypes
ryegrass
Effect of ferulic acid on growth of ryegrass
S.alba
Potency of two herbicides
S.capricornutum
Effect of cadmium on growth of green alga
searchdrc
Searching through a range of initial parameter values to...
secalonic
Root length measurements
selenium
Data from toxicology experiments with selenium
simDR
Simulating ED values under various scenarios
spinach
Inhibition of photosynthesis
summary.drc
Summarising non-linear model fits
terbuthylazin
The effect of terbuthylazin on growth rate
twophase
Two-phase dose-response model
update.drc
Updating and re-fitting a model
ursa
Model function for the universal response surface approach...
vcov.drc
Calculating variance-covariance matrix for objects of class...
vinclozolin
Vinclozolin from AR in vitro assay
W2
The two-parameter Weibull functions
W3
The three-parameter Weibull functions
W4
The four-parameter Weibull functions
weibull1
Weibull model functions
yieldLoss
Calculating yield loss parameters

Files in this package

drc
drc/inst
drc/inst/CITATION
drc/tests
drc/tests/test1.R
drc/tests/test1.w1.txt
drc/tests/test2.redroot_dose.csv
drc/tests/test3.R
drc/tests/test1.data1.txt
drc/tests/test2.R
drc/NAMESPACE
drc/NEWS
drc/data
drc/data/selenium.rda
drc/data/lettuce.rda
drc/data/metals.rda
drc/data/H.virescens.rda
drc/data/ryegrass.rda
drc/data/terbuthylazin.rda
drc/data/earthworms.rda
drc/data/algae.rda
drc/data/daphnids.rda
drc/data/mecter.rda
drc/data/germination.rda
drc/data/auxins.rda
drc/data/lepidium.rda
drc/data/vinclozolin.rda
drc/data/RScompetition.rda
drc/data/deguelin.rda
drc/data/P.promelas.rda
drc/data/leaflength.rda
drc/data/O.mykiss.rda
drc/data/etmotc.rda
drc/data/spinach.rda
drc/data/secalonic.rda
drc/data/decontaminants.rda
drc/data/chickweed.rda
drc/data/acidiq.rda
drc/data/M.bahia.rda
drc/data/heartrate.rda
drc/data/nasturtium.rda
drc/data/G.aparine.rda
drc/data/S.capricornutum.rda
drc/data/S.alba.rda
drc/data/chickweed0.rda
drc/data/methionine.rda
drc/data/finney71.rda
drc/data/glymet.rda
drc/R
drc/R/ED.drc.R
drc/R/weibull2.R
drc/R/mixture.R
drc/R/CRS.6.R
drc/R/baro5.R
drc/R/EDhelper.R
drc/R/residuals.drc.R
drc/R/gompertzd.R
drc/R/multi2.R
drc/R/anova.drclist.R
drc/R/fplogistic.R
drc/R/neill.test.R
drc/R/braincousens.R
drc/R/gaussian.R
drc/R/boxcox.drc.R
drc/R/lnormal.ssf.R
drc/R/drmLOFls.R
drc/R/gaussian.ssf.R
drc/R/rdrm.R
drc/R/siInner.R
drc/R/onAttach.R
drc/R/confint.drc.R
drc/R/lnormal.R
drc/R/plot.drc.R
drc/R/ED.lin.R
drc/R/PR.R
drc/R/yieldLoss.R
drc/R/drm.R
drc/R/logLik.drc.R
drc/R/mrdrm.R
drc/R/sandwich.R
drc/R/drmParNames.R
drc/R/print.drc.R
drc/R/hatvalues.drc.R
drc/R/isobole.R
drc/R/cooks.distance.drc.R
drc/R/predict.drc.R
drc/R/searchdrc.R
drc/R/hewlett.R
drc/R/weibull2x.R
drc/R/resPrint.R
drc/R/ucedergreen.R
drc/R/MAX.R
drc/R/getInitial.R
drc/R/CIcompX.R
drc/R/gompertz.R
drc/R/backfit.R
drc/R/noEffect.R
drc/R/cedergreen.R
drc/R/drmEMstandard.R
drc/R/findbe.R
drc/R/drmEMls.R
drc/R/llogistic.R
drc/R/commatFct.R
drc/R/drmRobust.R
drc/R/genRetFct.R
drc/R/mselect.R
drc/R/xlogx.R
drc/R/cedergreen.ssf.R
drc/R/NEC.R
drc/R/drmc.R
drc/R/summary.drc.R
drc/R/drmEMbinomial.R
drc/R/update.drc.R
drc/R/arandaordaz.R
drc/R/weibull1.R
drc/R/absToRel.R
drc/R/threephase.R
drc/R/drmConvertParm.R
drc/R/relpot.R
drc/R/drmPNsplit.R
drc/R/weibull1.ssf.R
drc/R/EDcomp.R
drc/R/fct2list.R
drc/R/gammadr.R
drc/R/lin.test.R
drc/R/rse.R
drc/R/weibull2.ssf.R
drc/R/maED.R
drc/R/mr.test.R
drc/R/ursa.R
drc/R/braincousens.ssf.R
drc/R/twophase.R
drc/R/drmOpt.R
drc/R/fitted.drc.R
drc/R/lgaussian.R
drc/R/llogistic.ssf.R
drc/R/logistic.ssf.R
drc/R/getMeanFunctions.R
drc/R/modelFunction.R
drc/R/compParm.R
drc/R/voelund.R
drc/R/iband.R
drc/R/simFct.R
drc/R/comped.R
drc/R/vcov.drc.R
drc/R/logistic.R
drc/R/gompertz.ssf.R
drc/R/Rsq.R
drc/R/coef.drc.R
drc/R/idrm.R
drc/R/findcd.R
drc/R/simDR.R
drc/R/drmEMeventtime.r
drc/R/drmEMPoisson.R
drc/R/modelFit.R
drc/R/pickParm.R
drc/R/repChar.R
drc/R/llogistic2.R
drc/R/showNews.R
drc/R/drmLOFbinomial.R
drc/R/anova.drc.R
drc/R/print.summary.drc.R
drc/MD5
drc/DESCRIPTION
drc/LICENCE
drc/man
drc/man/S.capricornutum.Rd
drc/man/compParm.Rd
drc/man/metals.Rd
drc/man/residuals.drc.Rd
drc/man/vcov.drc.Rd
drc/man/twophase.Rd
drc/man/lettuce.Rd
drc/man/braincousens.Rd
drc/man/mixture.Rd
drc/man/ryegrass.Rd
drc/man/EXD.Rd
drc/man/noEffect.Rd
drc/man/lin.test.Rd
drc/man/EDcomp.Rd
drc/man/gompertz.Rd
drc/man/baro5.Rd
drc/man/S.alba.Rd
drc/man/cedergreen.Rd
drc/man/modelFit.Rd
drc/man/G.aparine.Rd
drc/man/glymet.Rd
drc/man/getInitial.Rd
drc/man/AR.Rd
drc/man/predict.drc.Rd
drc/man/searchdrc.Rd
drc/man/getMeanFunctions.Rd
drc/man/CRS.4a.Rd
drc/man/O.mykiss.Rd
drc/man/acidiq.Rd
drc/man/barley.Rd
drc/man/MM.Rd
drc/man/H.virescens.Rd
drc/man/gaussian.Rd
drc/man/chickweed.Rd
drc/man/gammadr.Rd
drc/man/fitted.drc.Rd
drc/man/neill.test.Rd
drc/man/ursa.Rd
drc/man/print.summary.drc.Rd
drc/man/W2.Rd
drc/man/secalonic.Rd
drc/man/plot.drc.Rd
drc/man/NEC.Rd
drc/man/logistic.Rd
drc/man/summary.drc.Rd
drc/man/fplogistic.Rd
drc/man/coef.drc.Rd
drc/man/lnormal.Rd
drc/man/lepidium.Rd
drc/man/simDR.Rd
drc/man/RScompetition.Rd
drc/man/etmotc.Rd
drc/man/P.promelas.Rd
drc/man/rdrm.Rd
drc/man/heartrate.Rd
drc/man/boxcox.drc.Rd
drc/man/multi2.Rd
drc/man/weibull1.Rd
drc/man/MAX.Rd
drc/man/isobole.Rd
drc/man/nasturtium.Rd
drc/man/finney71.Rd
drc/man/backfit.Rd
drc/man/terbuthylazin.Rd
drc/man/mselect.Rd
drc/man/hatvalues.drc.Rd
drc/man/LL.3.Rd
drc/man/deguelin.Rd
drc/man/llogistic.Rd
drc/man/drmc.Rd
drc/man/algae.Rd
drc/man/CIcompX.Rd
drc/man/CRS.5a.Rd
drc/man/ED.drc.Rd
drc/man/W4.Rd
drc/man/confint.drc.Rd
drc/man/selenium.Rd
drc/man/W3.Rd
drc/man/comped.Rd
drc/man/LL.2.Rd
drc/man/germination.Rd
drc/man/auxins.Rd
drc/man/daphnids.Rd
drc/man/logLik.drc.Rd
drc/man/anova.drc.Rd
drc/man/PR.Rd
drc/man/maED.Rd
drc/man/mr.test.Rd
drc/man/M.bahia.Rd
drc/man/drm.Rd
drc/man/spinach.Rd
drc/man/update.drc.Rd
drc/man/LL.5.Rd
drc/man/gompertzd.Rd
drc/man/vinclozolin.Rd
drc/man/mecter.Rd
drc/man/earthworms.Rd
drc/man/decontaminants.Rd
drc/man/BC.Rd
drc/man/bread.drc.Rd
drc/man/LL.4.Rd
drc/man/yieldLoss.Rd
drc/man/print.drc.Rd
drc/man/methionine.Rd