getBootTaus: Run nonparametric bootstrap on the interaction index model

Description Usage Arguments Value Author(s)

View source: R/bootstrap.R

Description

Function to run nonparametric bootstrap on the interaction index model. It is usually called from getTauSurface.

Usage

1
2
3
4
5
6
7
8
getBootTaus(
  fit,
  niter = 100,
  resample = c("all", "mono", "stratified"),
  seed = NULL,
  verbose = FALSE,
  ...
)

Arguments

fit

A HarbronFit object returned by fitModel.

niter

Number of bootstrap samples to use.

resample

Resampling method for bootstrap. Either "all" (default) for resampling from all data, "mono" for separately resampling monotherapy and combination data, or "stratified" for resampling at each dose combination separately. Note that the latter method is not meaningful if there are no replicates in the data.

seed

Random seed to use for bootstrap

verbose

Whether to show progress information.

...

Further arguments passed to the fitModel calls.

Value

A matrix of interaction index estimates based on the bootstrap samples.

Author(s)

Maxim Nazarov


drugCombo documentation built on June 30, 2021, 1:07 a.m.