Description Usage Arguments Value
This function reads the synergy biomarker files inside the given directory and merges
the results into a data.frame
which it returns. This functions should
be used when the synergy biomarker results are in separate files inside the
directory given (see biomarkers.dir
parameter).
1 2 3 4 5 6 | get_synergy_biomarkers_from_dir(
predicted.synergies,
biomarkers.dir,
models.dir = NULL,
node.names = NULL
)
|
predicted.synergies |
a character vector of the synergies (drug combination names) that were predicted by at least one of the models in the dataset. |
biomarkers.dir |
string. It specifies the full path name of the
directory which holds the biomarker files (without the ending character
/). The biomarker files must be formatted as:
%drug.comb%_biomarkers_active or
%drug.comb%_biomarkers_inhibited, where %drug.comb% is an element
of the |
models.dir |
string. A directory with .gitsbe files/models. It's
needed in order to call |
node.names |
a character vector which has the names of the nodes. If it's
not NULL, then it will be used instead of the |
a data.frame, whose columns represent the network nodes and the rows the predicted synergies. Possible values for each synergy-node element are either 1 (active state biomarker), -1 (inhibited state biomarker) or 0 (not a biomarker or the node is not at all present in the network or the drug combination is not a synergistic one).
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