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#' Function to conduct marginal mediation analysis
#'
#'computes indirect effect using average marginal effects with bootstrapped standard errors
#' @param restricted.model is the model without the mediator variable(s)
#' @param full.model is the full model including all mediating variables
#' @param mediator is a mediating varaible or a character vector containing the names of the mediator variables if joint mediation is of interest
#' @param direct_substructural_effect is the direct effect of interest
ergm.msma<-function(restricted.model,
full.model,
direct_substructural_effect,
higher_order_term=NULL,
lower_order_term=NULL,
at.lower_order_term=NULL,
mediator,
at.controls=NULL,
control_vals=NULL,
estimate="aMSE"){
if(class(restricted.model)%in%"btergm"){
out<-ergm.msma_boot(restricted.model=restricted.model,
full.model=full.model,
direct_substructural_effect=direct_substructural_effect,
higher_order_term=higher_order_term,
lower_order_term=lower_order_term,
at.lower_order_term=at.lower_order_term,
mediator=mediator,
at.controls=at.controls,
control_vals=control_vals,
estimate=estimate)
return(out)
}
if(class(restricted.model)%in%"mlergm"){
theta1<-restricted.model$theta
theta2<-full.model$theta
}else{
theta1<-btergm::coef(restricted.model)
theta2<-btergm::coef(full.model)
}
##check at.controls appear in both models
if(!is.null(at.controls)){
if(!all(at.controls%in%names(theta1))){
stop("Variables specified in any.controls must appear in both models to be used.")
}
if(!all(at.controls%in%names(theta2))){
stop("Variables specified in any.controls must appear in both models to be used.")
}
}
# dse<-direct_substructural_effect
tot.MSE<-ergm.MSE(model=restricted.model,
substructural_effect=direct_substructural_effect,
higher_order_term=higher_order_term,
lower_order_term=lower_order_term,
at.lower_order_term=at.lower_order_term,
var2=NULL,
inter=NULL,
at.2=NULL,
at.controls=at.controls,
control_vals=control_vals,
estimate=estimate,
return_Jac=TRUE)
tot.Jac<-tot.MSE$Jac
tot.MSE<-tot.MSE$MSE
p.MSE<-ergm.MSE(model=full.model,
substructural_effect=direct_substructural_effect,
higher_order_term=higher_order_term,
lower_order_term=lower_order_term,
at.lower_order_term=at.lower_order_term,
var2=NULL,
inter=NULL,
at.2=NULL,
at.controls=at.controls,
control_vals=control_vals,
estimate=estimate,
return_Jac=TRUE)
p.Jac<-p.MSE$Jac
p.MSE<-p.MSE$MSE
###estimate cross-model covariance
names(p.Jac)<-names(theta2)
names(tot.Jac)<-names(theta1)
tot.Jac_expanded<-rep(0,length(p.Jac))
names(tot.Jac_expanded)<-names(p.Jac)
tot.Jac_expanded[names(tot.Jac_expanded)%in%names(tot.Jac)]<-tot.Jac
#get vcovs
if(class(restricted.model)%in%"mtergm"){
tot.vc <- stats::vcov(restricted.model@ergm)
tot.vc <-tot.vc[!rownames(tot.vc)%in%c("edgecov.offsmat","offset(edgecov.offsmat)"),
!colnames(tot.vc)%in%c("edgecov.offsmat","offset(edgecov.offsmat)")]
p.vc <- stats::vcov(full.model@ergm)
p.vc <-p.vc[!rownames(p.vc)%in%c("edgecov.offsmat","offset(edgecov.offsmat)"),
!colnames(p.vc)%in%c("edgecov.offsmat","offset(edgecov.offsmat)")]
}else{
tot.vc <- stats::vcov(restricted.model)
p.vc <- stats::vcov(full.model)
}
if(class(restricted.model)%in%"mlergm"){
tot.vc<-solve(tot.vc)
p.vc<-solve(p.vc)
}
tot_vc_expanded<-matrix(0,nrow=nrow(p.vc),ncol=ncol(p.vc))
rownames(tot_vc_expanded)<-colnames(tot_vc_expanded)<-names(theta2)
tot_vc_expanded[rownames(tot_vc_expanded)%in%names(theta1),
colnames(tot_vc_expanded)%in%names(theta1)]<-tot.vc
#calculate gradient and cross_mod covariance
cross_mod_grad<-t(p.Jac)%*%t(as.matrix(tot.Jac_expanded))
cross_mod_cov<-p.vc%*%cross_mod_grad%*%tot_vc_expanded
rownames(tot.MSE)<-paste("total effect:",rownames(tot.MSE))
rownames(p.MSE)<-paste("partial effect:",rownames(p.MSE))
###indirect effect
msma.me<-tot.MSE[1,1]-p.MSE[1,1]
cov.mse<-cross_mod_cov[direct_substructural_effect,direct_substructural_effect]
msma.se<-sqrt(tot.MSE[,2]^2+p.MSE[,2]^2-cov.mse)
msma.z<-msma.me/msma.se
p.msma<-2*stats::pnorm(-abs(msma.z))
ind<-matrix(signif(c(msma.me,msma.se,msma.z,p.msma),digits=5),nrow=1,ncol=4)
colnames(ind)<-colnames(tot.MSE)
if(length(mediator)>1) {
mediator<-paste(mediator,collapse=", ")}
rownames(ind)<-paste("indirect effect:",direct_substructural_effect,"->",mediator)
out<-rbind(tot.MSE,p.MSE,ind)
proportion.mediated<-1-(p.MSE[1]/tot.MSE[1])
attr(out,"description")<-paste("proportion of",direct_substructural_effect,"mediated by",mediator," = ",round(proportion.mediated,digits=3))
return(out)
}
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