Description Usage Arguments Details Value Author(s) See Also

View source: R/design.dichotomique.R

This function sets up two identical lists, each containing a design matrix for the linear predictor of the logit of a dichotomous outcome under a full logistic model with main effects and product terms for two biallelic markers.

1 |

`x` |
A 2-column matrix of numeric values representing genotypes of biallelic markers, with one column per marker and one row per subject. The two homozygous genotypes must be coded 0 and 1, and the heterozygous genotype value depends on the genetic model: 0 (recessive), 1/2 (allelic) or 1 (dominant). |

`...` |
Additional arguments will be ignored, but must be allowed for compatibility with other design functions. |

The linear predictors (without intercept) of the logistic function for *Y = 1* against the reference level *Y = 0* has the form:

*Y[1] = 1 , Y[2] = 0 : η[11] X[1] + η[12] X[2] + η[13] X[1] X[2]*

The design matrix for the above model is constructed by this function.

`x.e ` |
List containing the single design matrix with all terms forming the full 2-locus logistic model |

`x.loc.e ` |
list of character strings containing the indices of the variables in |

`x.l ` |
identical to |

`x.loc.l ` |
identical to |

Alexandre Bureau <alexandre.bureau@msp.ulaval.ca>

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