betablocker: Clinical Trial of Beta-Blockers
In flexmix: Flexible Mixture Modeling

betablocker

R Documentation

Clinical Trial of Beta-Blockers

Description

22-centre clinical trial of beta-blockers for reducing mortality after myocardial infarction.

Usage

data("betablocker")

Format

A data frame with 44 observations on the following 4 variables.

Deaths: Number of deaths.
Total: Total number of patients.
Center: Number of clinical centre.
Treatment: A factor with levels Control and Treated.

Source

G. McLachlan and D. Peel. Finite Mixture Models, 2000. John Wiley and Sons Inc. http://www.maths.uq.edu.au/~gjm/DATA/mmdata.html

References

M. Aitkin. Meta-analysis by random effect modelling in generalized linear models. Statistics in Medicine, 18, 2343–2351, 1999.

S. Yusuf, R. Peto, J. Lewis, R. Collins and P. Sleight. Beta blockade during and after myocardial infarction: an overview of the randomized trials. Progress in Cardiovascular Diseases, 27, 335–371, 1985.

Examples

data("betablocker", package = "flexmix")
betaMix <- initFlexmix(cbind(Deaths, Total - Deaths) ~ 1 | Center,
                       data = betablocker, k = 3, nrep = 5,
                       model = FLXMRglmfix(family = "binomial",
                         fixed = ~Treatment))

flexmix documentation built on March 31, 2023, 8:36 p.m.