colorectal: Follow-up of metastatic colorectal cancer patients: times of...
In frailtypack: Shared, Joint (Generalized) Frailty Models; Surrogate Endpoints
colorectal R Documentation
Follow-up of metastatic colorectal cancer patients: times of new lesions
appearance and death
Description
Randomly chosen 150 patients from the follow-up of the FFCD 2000-05
multicenter phase III clinical trial originally including 410 patients with
metastatic colorectal cancer randomized into two therapeutic strategies:
combination and sequential. The dataset contains times of observed
appearances of new lesions censored by a terminal event (death or
right-censoring) with baseline characteristics (treatment arm, age, WHO
performance status and previous resection).
Usage
data(colorectal)
Format
This data frame contains the following columns:
- id
identification of each subject. Repeated for each recurrence
- time0
start of interval (0 or previous recurrence time)
- time1
recurrence or censoring time
- new.lesions
Appearance of
new lesions status. 0: censsored or no event, 1: new lesions
- treatment
To which treatment arm a patient was allocated? 1:
sequential (S); 2: combination (C)
- age
Age at baseline: 1: <50
years, 2: 50-69 years, 3: >69 years
- who.PS
WHO performance status at
baseline: 1: status 0, 2: status 1, 3: status 2
- prev.resection
Previous resection of the primate tumor? 0: No, 1:
Yes
- state
death indicator. 0: alive, 1: dead
- gap.time
interocurrence time or censoring time
Note
We thank the Federation Francophone de Cancerologie Digestive and
Gustave Roussy for sharing the data of the FFCD 2000-05 trial supported by
an unrestricted Grant from Sanofi.
References
M. Ducreux, D. Malka, J. Mendiboure, P.-L. Etienne, P. Texereau,
D. Auby, P. Rougier, M. Gasmi, M. Castaing, M. Abbas, P. Michel, D. Gargot,
A. Azzedine, C. Lombard- Bohas, P. Geoffroy, B. Denis, J.-P., Pignon,
L.,Bedenne, and O. Bouche (2011). Sequential versus combination
chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05):
an open-label, randomised, phase 3 trial. The Lancet Oncology
12, 1032-44.
frailtypack documentation built on Nov. 25, 2023, 9:06 a.m.
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| colorectal | R Documentation |
Follow-up of metastatic colorectal cancer patients: times of new lesions appearance and death
Description
Randomly chosen 150 patients from the follow-up of the FFCD 2000-05 multicenter phase III clinical trial originally including 410 patients with metastatic colorectal cancer randomized into two therapeutic strategies: combination and sequential. The dataset contains times of observed appearances of new lesions censored by a terminal event (death or right-censoring) with baseline characteristics (treatment arm, age, WHO performance status and previous resection).
Usage
data(colorectal)
Format
This data frame contains the following columns:
- id
identification of each subject. Repeated for each recurrence
- time0
start of interval (0 or previous recurrence time)
- time1
recurrence or censoring time
- new.lesions
Appearance of new lesions status. 0: censsored or no event, 1: new lesions
- treatment
To which treatment arm a patient was allocated? 1: sequential (S); 2: combination (C)
- age
Age at baseline: 1: <50 years, 2: 50-69 years, 3: >69 years
- who.PS
WHO performance status at baseline: 1: status 0, 2: status 1, 3: status 2
- prev.resection
Previous resection of the primate tumor? 0: No, 1: Yes
- state
death indicator. 0: alive, 1: dead
- gap.time
interocurrence time or censoring time
Note
We thank the Federation Francophone de Cancerologie Digestive and Gustave Roussy for sharing the data of the FFCD 2000-05 trial supported by an unrestricted Grant from Sanofi.
References
M. Ducreux, D. Malka, J. Mendiboure, P.-L. Etienne, P. Texereau, D. Auby, P. Rougier, M. Gasmi, M. Castaing, M. Abbas, P. Michel, D. Gargot, A. Azzedine, C. Lombard- Bohas, P. Geoffroy, B. Denis, J.-P., Pignon, L.,Bedenne, and O. Bouche (2011). Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): an open-label, randomised, phase 3 trial. The Lancet Oncology 12, 1032-44.
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