colorectalLongi: Follow-up of metastatic colorectal cancer patients :...
In frailtypack: Shared, Joint (Generalized) Frailty Models; Surrogate Endpoints
colorectalLongi R Documentation
Follow-up of metastatic colorectal cancer patients : longitudinal
measurements of tumor size
Description
Randomly chosen 150 patients from the follow-up of the FFCD 2000-05
multicenter phase III clinical trial originally including 410 patients with
metastatic colorectal cancer randomized into two therapeutic strategies:
combination and sequential. The dataset contains measurements of tumor size
(left-censored sums of the longest diameters of target lesions; transformed
using Box-Cox) with baseline characteristics(treatment arm, age, WHO
performance status and previous resection).
Usage
data(colorectalLongi)
Format
This data frame contains the following columns:
- id
identification of each subject. Repeated for each recurrence
- year
time of visit counted in years from baseline
- tumor.size
Individual longitudinal measurement of transformed
(Box-Cox with parameter 0.3) sums of the longest diameters, left-censored
due to a detection limit (threshold s=-3.33).
- treatment
To
which treatment arm a patient was allocated? 1: sequential (S); 2:
combination (C)
- age
Age at baseline: 1: <50 years, 2: 50-69 years,
3: >69 years
- who.PS
WHO performance status at baseline: 1: status 0,
2: status 1, 3: status 2
- prev.resection
Previous resection of the
primate tumor? 0: No, 1: Yes
Note
We thank the Federation Francophone de Cancerologie Digestive and
Gustave Roussy for sharing the data of the FFCD 2000-05 trial supported by
an unrestricted Grant from Sanofi.
References
Ducreux, M., Malka, D., Mendiboure, J., Etienne, P.-L.,
Texereau, P., Auby, D., Rougier, P., Gasmi, M., Castaing, M., Abbas, M.,
Michel, P., Gargot, D., Azzedine, A., Lombard- Bohas, C., Geoffroy, P.,
Denis, B., Pignon, J.-P., Bedenne, L., and Bouche, O. (2011). Sequential
versus combination chemotherapy for the treatment of advanced colorectal
cancer (FFCD 2000-05): an open-label, randomised, phase 3 trial. The
Lancet Oncology 12, 1032-44.
frailtypack documentation built on Nov. 25, 2023, 9:06 a.m.
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| colorectalLongi | R Documentation |
Follow-up of metastatic colorectal cancer patients : longitudinal measurements of tumor size
Description
Randomly chosen 150 patients from the follow-up of the FFCD 2000-05 multicenter phase III clinical trial originally including 410 patients with metastatic colorectal cancer randomized into two therapeutic strategies: combination and sequential. The dataset contains measurements of tumor size (left-censored sums of the longest diameters of target lesions; transformed using Box-Cox) with baseline characteristics(treatment arm, age, WHO performance status and previous resection).
Usage
data(colorectalLongi)
Format
This data frame contains the following columns:
- id
identification of each subject. Repeated for each recurrence
- year
time of visit counted in years from baseline
- tumor.size
Individual longitudinal measurement of transformed (Box-Cox with parameter 0.3) sums of the longest diameters, left-censored due to a detection limit (threshold
s=-3.33).- treatment
To which treatment arm a patient was allocated? 1: sequential (S); 2: combination (C)
- age
Age at baseline: 1: <50 years, 2: 50-69 years, 3: >69 years
- who.PS
WHO performance status at baseline: 1: status 0, 2: status 1, 3: status 2
- prev.resection
Previous resection of the primate tumor? 0: No, 1: Yes
Note
We thank the Federation Francophone de Cancerologie Digestive and Gustave Roussy for sharing the data of the FFCD 2000-05 trial supported by an unrestricted Grant from Sanofi.
References
Ducreux, M., Malka, D., Mendiboure, J., Etienne, P.-L., Texereau, P., Auby, D., Rougier, P., Gasmi, M., Castaing, M., Abbas, M., Michel, P., Gargot, D., Azzedine, A., Lombard- Bohas, C., Geoffroy, P., Denis, B., Pignon, J.-P., Bedenne, L., and Bouche, O. (2011). Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): an open-label, randomised, phase 3 trial. The Lancet Oncology 12, 1032-44.
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